Osteoarthritis (OA) is a degenerative joint disease characterized by low-grade inflammation
and high levels of clinical heterogeneity. Aberrant chondrocyte metabolism is a response to …

Nitric oxide (NO) is a small free radical with critical signaling roles in physiology and
pathophysiology. The generation of sufficient NO levels to regulate the resistance of the …

As a functional amino acid (AA), L-arginine (Arg) serves not only as a building block of
protein but also as an essential substrate for the synthesis of nitric oxide (NO), creatine …

Cancer cell metabolism is heavily influenced by microenvironmental factors, including
nutrient availability. Therefore, knowledge of microenvironmental nutrient levels is essential …

Wound healing implicates several biological and molecular events, such as coagulation,
inflammation, migration-proliferation, and remodeling. Here, we provide an overview of the …

Hemp (Cannabis sativa L.) seeds have been consumed in Asian communities since
prehistoric times. Recently, Australia, Canada, and the United States have legalized the …

Thirty years after the discovery of its production by activated macrophages, our appreciation
of the diverse roles of nitric oxide (NO) continues to grow. Recent findings have not only …

Mammalian arginine metabolism is complex due to the expression of multiple enzymes that
utilize arginine as substrate and to interactions or competition between specific enzymes …

Animals are biological transformers of dietary matter and energy to produce high-quality
foods and wools for human consumption and use. Mammals, birds, fish, and shrimp require …

Nutrition plays an essential role in the regulation of optimal immunological response, by
providing adequate nutrients in sufficient concentrations to immune cells. There are a large …