Ligand-Enabled Cu-Catalyzed Stereoselective Synthesis of P-Stereogenic ProTides

SS Fang, XJ Hu, MH Li, S Qi, T Xie… - Journal of the …, 2024 - ACS Publications
Nucleoside analogues have seen significant advancements in treating viral infections and
cancer through ProTide technology, leading to a series of FDA-approved drugs such as …

[HTML][HTML] Transition-metal-catalyzed aromatic C–H functionalization assisted by the phosphorus-containing directing groups

J Zhang, L Yao, JY Su, YZ Liu, Q Wang… - Green Synthesis and …, 2023 - Elsevier
Transition-metal-catalyzed C–H bond functionalization has attracted tremendous attention
as an increasingly important protocol for the construction of C–C and C–X bonds. In …

Aggregation-induced polarization (AIP) of derivatives of BINOL and BINAP

Y Tang, Q Yuan, Y Wang, S Zhang, JY Wang, S Jin… - RSC …, 2022 - pubs.rsc.org
The relationship between optical rotations of small chiral molecules with water% in THF has
been established. The typical aggregation co-solvent systems resulted in optical rotation …

Direct Synthesis of ortho-Halogenated Arylphosphonates via a Three-Component Reaction Involving Arynes

Y Huang, Y Hu, Y Han, Y Ou, Y Huo, X Li… - The Journal of Organic …, 2021 - ACS Publications
A three-component reaction involving arynes, trialkyl phosphites, and halides has been
achieved under mild reaction conditions. This transformation provides a direct synthetic …

An Electrochemical Method for Deborylative Hydroxylation of Arylboronic Acids under Metal‐free Conditions

Z Fu, X Yi, Z Fang, T Zhong, D He… - Chemistry–An Asian …, 2022 - Wiley Online Library
An electrochemical method for the synthesis of (poly) phenols via deborylative hydroxylation
of arylborons has been well established under metal‐free conditions, whose practicability …

β-Carboline directed regioselective hydroxylation by employing Cu (OAc) 2 and mechanistic investigation by ESI-MS

D Bora, R Tokala, SE John, B Prasanth… - Organic & …, 2020 - pubs.rsc.org
A β-carboline directed regioselective C–H activation protocol for hydroxylation has been
developed by employing Cu (OAc) 2, a cost-effective 3d metal. This fastidious reaction …

Nickel-catalyzed coupling of R 2 P (O) Me (R= aryl or alkoxy) with (hetero) arylmethyl alcohols

WZ Li, ZX Wang - Organic & Biomolecular Chemistry, 2021 - pubs.rsc.org
α-Alkylation of methyldiarylphosphine oxides with (hetero) arylmethyl alcohols was
performed under nickel catalysis. Various arylmethyl and heteroarylmethyl alcohols can be …

Microwave‐Assisted Ruthenium‐ and Rhodium‐Catalyzed Couplings of α‐Amino Acid Ester‐Derived Phosphinamides with Alkynes

XH Li, JF Gong, MP Song - Chemistry–An Asian Journal, 2022 - Wiley Online Library
Two different types of new phosphinamide α‐amino ester derivatives have been prepared in
moderate to high yields via ruthenium (II) and rhodium (III)‐catalyzed ortho‐C− H …

铜参与的烯基酰胺β-碳氢键与端炔的炔基化反应

孙尚政, 王星, 程泰锦, 徐辉, 戴辉雄 - 有机化学, 2020 - sioc-journal.cn
有机化学 Page 1 有机化学 Chinese Journal of Organic Chemistry ARTICLE * Corresponding
author. E-mail: hxdai@simm.ac.cn Received May 23, 2020; revised June 20, 2020; published …

Palladium-catalyzed aminocarbonylation of aryl iodides with amines: efficient access to bidentate amide directing groups

Y Wang, T Wang, X Wang, L Liu, G Mao - Transition Metal Chemistry, 2021 - Springer
A new route to bidentate amide directing groups has been developed via the palladium (II)-
catalyzed aminocarbonylation. Under atmospheric carbon monoxide pressure, using …