Our aim is to present an updated overview of the erythrocyte metabolism highlighting its
richness and complexity. We have manually collected and connected the available …

Targeted delivery of vaccines to the spleen remains a challenge. Inspired by the
erythrophagocytotic process in the spleen, we herein report that intravenous administration …

Redox imbalance and oxidative stress have emerged as generative causes of the structural
and functional degradation of red blood cells (RBC) that happens during their hypothermic …

Red blood cells (RBCs) change shape and deformability with age, making them more likely
to be trapped in the splenic slits (IESs) and removed from circulation. Existing evidence …

The splenic interendothelial slits fulfill the essential function of continuously filtering red
blood cells (RBCs) from the bloodstream to eliminate abnormal and aged cells. To date, the …

Mechanical properties of red blood cells (RBCs) change during their senescence which
supports numerous physiological or pathological processes in circulatory systems by …

The biomimetic strategy has been widely used in multiple fields, and provides huge
convenience to human life. For biomedical application in vivo, the importance of biomimetic …

The excessive inflammatory response is known to be a major challenge for diabetic wound
healing, while bacteria secreted toxin, α-hemolysin (Hlα), was recently reported to prolong …

The repair of large bone defects poses a significant challenge in orthopedics.
Polyetheretherketone (PEEK) is a promising bone substitute, while it suffers a lack of …

Introduction Cranial and upper-airway anatomy of short-nosed, flat-faced brachycephalic
dogs predisposes them to brachycephalic obstructive airway syndrome (BOAS). Periodic …