Eggs and sperm develop through a specialized cell division called meiosis. During meiosis,
the number of chromosomes is reduced by two sequential divisions in preparation for …

Objective To study whether preimplantation genetic screening with comprehensive
chromosome screening (PGS-CCS) improves clinical implantation rates (IR) and sustained …

Aneuploidy is a hallmark of cancer and a major cause of miscarriages in humans. It is
caused by chromosome segregation errors during cell divisions. Evidence is mounting that …

Designed to minimize chances of transferring genetically abnormal embryos,
preimplantation genetic diagnosis (PGD) involves in vitro fertilization (IVF), embryo biopsy …

BACKGROUND Meiotic chromosome segregation in human oocytes is notoriously error-
prone, especially with ageing. Such errors markedly reduce the reproductive chances of …

Recently, 2 branches of the wide area of synthetic biology—in vitro gametogenesis and
synthetic embryo development—have gained considerable attention. Rodent induced …

The aim of this pilot study was to assess if array comparative genomic hybridization (aCGH),
non-invasive preimplantation genetic screening (PGS) on blastocyst culture media is …

During the last few years a new generation of preimplantation genetic screening (PGS) has
been introduced. In this paper, an overview of the different aspects of this so-called PGS 2.0 …

Abstract Background Recently, the Japan Society of Obstetrics and Gynecology initiated a
clinical study of preimplantation genetic test for aneuploidy. There will be a great need for a …

Background Chromosomal mosaicism is observed as the presence of both euploid and
aneuploid cells in a particular blastocyst. Recent studies have reported that the implantation …