Non-alcoholic fatty liver disease (NAFLD) is currently the world's most common liver
disease, estimated to affect up to one-fourth of the population. Hallmarked by hepatic …

Triglyceride molecules represent the major form of storage and transport of fatty acids within
cells and in the plasma. The liver is the central organ for fatty acid metabolism. Fatty acids …

Carnitine is essential for the transfer of long-chain fatty acids across the inner mitochondrial
membrane for subsequent β-oxidation. It can be synthesized by the body or assumed with …

The liver is an essential metabolic organ, and its metabolic activity is tightly controlled by
insulin and other metabolic hormones. Glucose is metabolized into pyruvate through …

CD36/FAT (fatty acid translocase) is associated with human and murine nonalcoholic fatty
liver disease, but it has been unclear whether it is simply a marker or whether it directly …

With nonalcoholic steatohepatitis (NASH), NASH cirrhosis, and NASH-related hepatocellular
carcinoma becoming increasingly prevalent, the need for effective therapies has never been …

In mammals, liver is a central organ for controlling the metabolic homeostasis for
carbohydrates, lipid, and proteins. Dysregulation of liver functions could lead to the …

Nonalcoholic fatty liver disease (NAFLD) affects about 30% of the general population in the
United States and includes a spectrum of disease that includes simple steatosis, non …

Lipids are vital components of many biological processes and crucial in the pathogenesis of
numerous common diseases, but the specific mechanisms coupling intracellular lipids to …

Fatty acid-binding proteins (FABPs) are members of the intracellular lipid-binding protein
(iLBP) family and are involved in reversibly binding intracellular hydrophobic ligands and …