The transition from normal to chronic pain is believed to involve alterations in several brain
areas that participate in the perception of pain. These plastic changes are then responsible …

Oxytocin (OT), a nonapeptide, has a variety of functions. Despite extensive studies on OT
over past decades, our understanding of its neural functions and their regulation remains …

The human species possesses two complementary, yet distinct, universal communication
systems—language and music. Functional imaging studies have revealed that some core …

Objective Acupuncture is a complex multicomponent treatment that has shown promise in
the treatment of fibromyalgia (FM). However, clinical trials have shown mixed results …

Heart failure (HF) in the elderly is an increasingly large and complex problem in modern
society. Notably, the cause of HF with preserved ejection fraction (HFpEF) is multifactorial …

Background and Purpose Chemotherapy‐induced neuropathic pain (CINP) currently has
limited effective treatment. Although the roles of oxytocin (OXT) and the oxytocin receptor …

Nociception is the neuronal process of encoding noxious stimuli and could be modulated at
peripheral, spinal, brainstem, and cortical levels. At cortical levels, several areas including …

Neuropathic pain is difficult to cure and is often accompanied by emotional and
psychological changes. Exploring the mechanisms underlying neuropathic pain will help to …

The hypothalamic neuropeptide oxytocin (OT) exerts prominent analgesic effects via central
and peripheral action. However, the precise analgesic pathways recruited by OT are largely …

Pleasant sensation is an underexplored avenue for modulation of chronic pain. Deeper
pressure is perceived as pleasant and calming, and can improve sleep. Although pressure …