Calcium channels, synaptic plasticity, and neuropsychiatric disease

E Nanou, WA Catterall - Neuron, 2018 - cell.com
Voltage-gated calcium channels couple depolarization of the cell-surface membrane to entry
of calcium, which triggers secretion, contraction, neurotransmission, gene expression, and …

Voltage gated sodium and calcium channels: Discovery, structure, function, and Pharmacology

WA Catterall - Channels, 2023 - Taylor & Francis
Voltage-gated sodium channels initiate action potentials in nerve and muscle, and voltage-
gated calcium channels couple depolarization of the plasma membrane to intracellular …

[图书][B] Principles of neural design

P Sterling, S Laughlin - 2015 - books.google.com
Neuroscience research has exploded, with more than fifty thousand neuroscientists applying
increasingly advanced methods. A mountain of new facts and mechanisms has emerged …

Essential thalamic contribution to slow waves of natural sleep

F David, JT Schmiedt, HL Taylor, G Orban… - Journal of …, 2013 - Soc Neuroscience
Slow waves represent one of the prominent EEG signatures of non-rapid eye movement
(non-REM) sleep and are thought to play an important role in the cellular and network …

Locus coeruleus activation enhances thalamic feature selectivity via norepinephrine regulation of intrathalamic circuit dynamics

C Rodenkirch, Y Liu, BJ Schriver, Q Wang - Nature neuroscience, 2019 - nature.com
We investigated locus coeruleus (LC) modulation of thalamic feature selectivity through
reverse correlation analysis of single-unit recordings from different stages of the rat vibrissa …

Cortical drive and thalamic feed-forward inhibition control thalamic output synchrony during absence seizures

C McCafferty, F David, M Venzi, ML Lőrincz… - Nature …, 2018 - nature.com
Behaviorally and pathologically relevant cortico-thalamo-cortical oscillations are driven by
diverse interacting cell-intrinsic and synaptic processes. However, the mechanism that gives …

T-Type Ca2+ Channels in Normal and Abnormal Brain Functions

E Cheong, HS Shin - Physiological reviews, 2013 - journals.physiology.org
Low-voltage-activated T-type Ca2+ channels are widely expressed in various types of
neurons. Once deinactivated by hyperpolarization, T-type channels are ready to be activated …

Human assembloids reveal the consequences of CACNA1G gene variants in the thalamocortical pathway

J Kim, Y Miura, MY Li, O Revah, S Selvaraj, F Birey… - Neuron, 2024 - cell.com
Abnormalities in thalamocortical crosstalk can lead to neuropsychiatric disorders. Variants in
CACNA1G, which encodes the α1G subunit of the thalamus-enriched T-type calcium …

Morpho-electric properties and diversity of oxytocin neurons in paraventricular nucleus of hypothalamus in female and male mice

S Chen, H Xu, S Dong, L Xiao - Journal of Neuroscience, 2022 - Soc Neuroscience
Oxytocin (OXT) neurons in paraventricular nucleus of hypothalamus (PVN) are involved in
modulating multiple functions, including social, maternal, feeding, and emotional related …

Cortical control of adaptation and sensory relay mode in the thalamus

RA Mease, P Krieger, A Groh - Proceedings of the National …, 2014 - National Acad Sciences
A major synaptic input to the thalamus originates from neurons in cortical layer 6 (L6);
however, the function of this cortico–thalamic pathway during sensory processing is not well …