Regional anesthesia in the patient receiving antithrombotic or thrombolytic therapy: American Society of Regional Anesthesia and Pain Medicine Evidence-Based …

TT Horlocker, E Vandermeuelen, SL Kopp… - Obstetric Anesthesia …, 2019 - journals.lww.com
The American Society of Regional Anesthesia and Pain Medicine (ASRA) convened its
Fourth Consensus Conference on Regional Anesthesia and Anticoagulation in conjunction …

2014 AHA/ACC/HRS guideline for the management of patients with atrial fibrillation: a report of the American College of Cardiology/American Heart Association Task …

CT January, LS Wann, JS Alpert, H Calkins… - Journal of the American …, 2014 - jacc.org
The recommendations listed in this document are, whenever possible, evidence based. An
extensive evidence review was conducted, focusing on 2006 through October 2012 and …

2014 AHA/ACC/HRS guideline for the management of patients with atrial fibrillation: executive summary: a report of the American College of Cardiology/American …

CT January, LS Wann, JS Alpert, H Calkins… - Circulation, 2014 - Am Heart Assoc
The recommendations listed in this document are, whenever possible, evidence based. An
extensive evidence review was conducted, focusing on 2006 through October 2012 and …

Specific antidotes against direct oral anticoagulants: a comprehensive review of clinical trials data

R Tummala, A Kavtaradze, A Gupta… - International journal of …, 2016 - Elsevier
The Vitamin K antagonist warfarin was the only oral anticoagulant available for decades for
the treatment of thrombosis and prevention of thromboembolism until Direct Oral …

Direct-acting oral anticoagulants and their reversal agents—an update

SA Kustos, PS Fasinu - Medicines, 2019 - mdpi.com
Background: Over the last ten years, a new class of drugs, known as the direct-acting oral
anticoagulants (DOACs), have emerged at the forefront of anticoagulation therapy. Like the …

Pharmacological properties of betrixaban

MV Huisman, FA Klok - European Heart Journal Supplements, 2018 - academic.oup.com
Venous thromboembolism (VTE) in acute medically ill patients is a leading cause of in-
hospital morbidity and mortality. A majority of these VTE events occur post-discharge, and …

Anticoagulants: pharmacokinetics, mechanisms of action, and indications

TA DeWald, JB Washam… - Neurosurgery …, 2018 - neurosurgery.theclinics.com
Patients requiring neurosurgical procedures, including elective and emergent surgery, are
often receiving an anticoagulant for a non-neurosurgical indication, such as atrial fibrillation …

Liquid chromatographic methods for the determination of direct oral anticoagulant drugs in biological samples: A critical review

F Gouveia, J Bicker, J Gonçalves, G Alves, A Falcão… - Analytica chimica …, 2019 - Elsevier
Direct oral anticoagulants (DOACs) are first-line drugs used for the treatment of venous
thromboembolism and prevention of stroke in patients with atrial fibrillation. These drugs do …

Contemporary developments in the discovery of selective factor Xa inhibitors: A review

NR Patel, DV Patel, PR Murumkar, MR Yadav - European journal of …, 2016 - Elsevier
Thrombosis is a leading cause of death in cardiovascular diseases such as myocardial
infarction (MI), unstable angina and acute coronary syndrome (ACS) in the industrialized …

[HTML][HTML] Betrixaban (Bevyxxa): A direct-acting oral anticoagulant factor Xa inhibitor

JW Skelley, AR Thomason, JC Nolen - Pharmacy and Therapeutics, 2018 - ncbi.nlm.nih.gov
Venous thromboembolism (VTE), including deep vein thrombosis (DVT) and pulmonary
embolism (PE), remains a preventable cause of morbidity and mortality in hospitalized …