Abstract Background Tandem repeats (TRs) are unstable regions commonly found within
genomes that have consequences for evolution and disease. In humans, polymorphic TRs …

Background Eukaryotic promoters are regions containing various sequence motifs
necessary to control gene transcription. Much evidence has emerged showing that structural …

The human genome harbors an abundance of repetitive DNA; however, its function
continues to be debated. Microsatellites—a class of short tandem repeat—are established …

Microsatellites–a type of short tandem repeat (STR)–have been used for decades as
putatively neutral markers to study the genetic structure of diverse human populations …

African American woman are 43% more likely to die from breast cancer than white women
and have increased the risk of tumor recurrence despite lower incidence. We investigate …

Background The germline genetic events underpinning medulloblastoma (MB) initiation,
and therefore the ability to determine who is at risk, are still unknown for the majority of …

Due to the lack of high-throughput genetic assays for tandem repeats, there is a paucity of
knowledge about the role they may play in disease. A polymorphic CA repeat in the …