Neuron-specific enolase as a biomarker: biochemical and clinical aspects

MA Isgrò, P Bottoni, R Scatena - … in cancer biomarkers: from biochemistry to …, 2015 - Springer
Neuron-specific enolase (NSE) is known to be a cell specific isoenzyme of the glycolytic
enzyme enolase. In vertebrate organisms three isozymes of enolase, expressed by different …

Update on inflammatory biomarkers and treatments in ischemic stroke

A Bonaventura, L Liberale, A Vecchié… - International journal of …, 2016 - mdpi.com
After an acute ischemic stroke (AIS), inflammatory processes are able to concomitantly
induce both beneficial and detrimental effects. In this narrative review, we updated evidence …

Blood biomarkers for detection of brain injury in COVID-19 patients

ST DeKosky, PM Kochanek, AB Valadka… - Journal of …, 2021 - liebertpub.com
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) virus attacks multiple
organs of coronavirus disease 2019 (COVID-19) patients, including the brain. There are …

Biomarkers for acute diagnosis and management of stroke in neurointensive care units

OY Glushakova, AV Glushakov, ER Miller… - Brain …, 2016 - journals.lww.com
The effectiveness of current management of critically ill stroke patients depends on rapid
assessment of the type of stroke, ischemic or hemorrhagic, and on a patient's general …

Neuron-specific enolase in hypertension patients with acute ischemic stroke and its value forecasting long-term functional outcomes

L Gao, J Xie, H Zhang, H Zheng, W Zheng, C Pang… - BMC geriatrics, 2023 - Springer
Abstract Background Neuron Specific Enolase (NSE), a neuro-biochemical protein marker,
may correlate with the prognosis of stroke patients. Moreover, hypertension is the most …

Effects of stellate ganglion block on early brain injury in patients with subarachnoid hemorrhage: a randomised control trial

J Zhang, Y Nie, Q Pang, X Zhang, Q Wang, J Tang - BMC anesthesiology, 2021 - Springer
Background Subarachnoid hemorrhage (SAH) is a common neurosurgical emergency, and
early brain injury (EBI) plays an important role in acute brain injury of SAH. Our objective is …

Predicting functional outcome of ischemic stroke patients in Romania based on plasma CRP, sTNFR-1, D-Dimers, NGAL and NSE measured using a biochip array

A Huţanu, M Iancu, R Bălaşa, S Maier… - Acta pharmacologica …, 2018 - nature.com
In cerebral ischemia, evaluation of multiple biomarkers involved in various pathological
pathways is a useful tool in assessing the outcome of the patients even from the early stages …

Effect of memantine on serum levels of neuron‐specific enolase and on the Glasgow Coma Scale in patients with moderate traumatic brain injury

M Mokhtari, H Nayeb‐Aghaei… - The Journal of …, 2018 - Wiley Online Library
Traumatic brain injury (TBI) is a major cause of disability and death globally. Despite
significant progress in neuromonitoring and neuroprotection, pharmacological interventions …

[HTML][HTML] Blood Biomarkers of the neurovascular unit in cerebrovascular disease and vascular cognitive disorders: A Systematic Review and Meta-Analysis

GK Hansra, T Jayasena, S Hosoki, A Poljak… - … -Cognition and Behavior, 2024 - Elsevier
Background The disruption of the neurovascular unit (NVU), which maintains the integrity of
the blood brain barrier (BBB), has been identified as a critical mechanism in the …

Cerebrospinal Fluid and Serum Biomarker Insights in Aneurysmal Subarachnoid Haemorrhage: Navigating the Brain–Heart Interrelationship for Improved Patient …

M Burzyńska, A Uryga, R Załuski, A Goździk, B Adamik… - Biomedicines, 2023 - mdpi.com
The pathophysiological mechanisms underlying severe cardiac dysfunction after
aneurysmal subarachnoid haemorrhage (aSAH) remain poorly understood. In the present …