Prevalence, risk, and challenges of extemporaneous preparation for pediatric patients in developing nations: A review

SH Yuliani, DCA Putri, DM Virginia, MR Gani… - Pharmaceutics, 2023 - mdpi.com
Extemporaneous preparations are still widely prescribed for pediatric patients with special
treatments of certain doses and/or combinations of drugs. Several problems related to …

[HTML][HTML] Orally disintegrating drug carriers for paediatric pharmacotherapy

EA Kean, OA Adeleke - European Journal of Pharmaceutical Sciences, 2023 - Elsevier
Non-compliance, dosing inaccuracy, choking risk, flavour, and instability, are some of the
issues associated with paediatric, oral dosage forms—tablets, capsules, solutions, and …

A review on taste masked multiparticulate dosage forms for paediatric

ALJ Khater, SH Almurisi, S Mahmood… - International journal of …, 2023 - Elsevier
Taste refers to those sensations perceived through taste buds on the tongue and oral cavity.
The unpleasant taste of drugs leads to the refusal of taking the medicine in the paediatric …

Self-assembled aluminum oxyhydroxide nanorices with superior suspension stability for vaccine adjuvant

S Bi, M Li, Z Liang, G Li, G Yu, J Zhang, C Chen… - Journal of Colloid and …, 2022 - Elsevier
The suspension stability of aluminum-based adjuvant (Alum) plays an important role in
determining the Alum-antigen interaction and vaccine efficacy. Inclusion of excipients has …

Development of a hydroxypropyl-β-cyclodextrin-based liquid formulation for the oral administration of propranolol in pediatric therapy

M Cirri, P Mura, S Benedetti, S Buratti - Pharmaceutics, 2023 - mdpi.com
Propranolol (PPN) is widely used in children to treat various cardiovascular diseases. The
availability of a suitable PPN solution should avoid recourse to extemporaneous …

A systematic review of the stability of extemporaneous pediatric oral formulations

A Belayneh, Z Tessema - The Scientific World Journal, 2021 - Wiley Online Library
Background. Extemporaneous compounding is a pharmacy practice to produce suitable
pharmaceutical preparations when there are no commercially available, licensed, and age …

The current states, challenges, ongoing efforts, and future perspectives of pharmaceutical excipients in pediatric patients in each country and region

J Saito, A Agrawal, V Patravale, A Pandya, S Orubu… - Children, 2022 - mdpi.com
A major hurdle in pediatric formulation development is the lack of safety and toxicity data on
some of the commonly used excipients. While the maximum oral safe dose for several kinds …

Acceptability of different oral dosage forms in paediatric patients in hospital setting

V Pokharkar, M Sajith, T Vallet, S Akshantal… - Archives of Disease in …, 2022 - adc.bmj.com
Objective The understanding of acceptability of existing dosage forms is limited in most of
the world and hinders the development of acceptable, age‐appropriate medicines. The …

Regulations on excipients used in 3D printing of pediatric oral forms

M Monteil, NM Sanchez-Ballester… - International Journal of …, 2024 - Elsevier
A promising solution to customize oral drug formulations for the pediatric population has
been found in the use of 3D printing, in particular Fused Deposition Modeling (FDM) and …

[HTML][HTML] Development of an oral liquid formulation of nicardipine hydrochloride compounded with simple excipients for the treatment of pediatric hypertension

M Cavelier, H Gondé, D Costa, F Lamoureux, T Pereira… - Pharmaceutics, 2023 - mdpi.com
Nicardipine hydrochloride is an anti-hypertensive drug that is used off-label to treat
hypertension in children. A previous oral formulation of nicardipine hydrochloride was …