Modern tools for rapid diagnostics of antimicrobial resistance

A Vasala, VP Hytönen, OH Laitinen - Frontiers in cellular and infection …, 2020 - frontiersin.org
Fast, robust, and affordable antimicrobial susceptibility testing (AST) is required, as roughly
50% of antibiotic treatments are started with wrong antibiotics and without a proper …

SERS-based antibiotic susceptibility testing: Towards point-of-care clinical diagnosis

NE Dina, MA Tahir, SZ Bajwa, I Amin, VK Valev… - Biosensors and …, 2023 - Elsevier
Emerging antibiotic resistant bacteria constitute one of the biggest threats to public health.
Surface-enhanced Raman scattering (SERS) is highly promising for detecting such bacteria …

Evaluation of Rapid Sepsityper® protocol and specific MBT-Sepsityper module (Bruker Daltonics) for the rapid diagnosis of bacteremia and fungemia by MALDI-TOF …

L Ponderand, P Pavese, D Maubon, E Giraudon… - Annals of Clinical …, 2020 - Springer
During bloodstream infections, rapid adaptation of empirical treatment according to the
microorganism identified is essential to decrease mortality. The aim of the present study was …

Burden of bacterial bloodstream infections and recent advances for diagnosis

SP Costa, CM Carvalho - Pathogens and Disease, 2022 - academic.oup.com
Bloodstream infections (BSIs) and subsequent organ dysfunction (sepsis and septic shock)
are conditions that rank among the top reasons for human mortality and have a great impact …

[HTML][HTML] A microfluidic platform combined with bacteriophage receptor binding proteins for multiplex detection of Escherichia coli and Pseudomonas aeruginosa in …

SP Costa, CRF Caneira, V Chu, PP Freitas… - Sensors and Actuators B …, 2023 - Elsevier
Bloodstream infections (BSIs) are triggered by the existence of pathogens in blood and are
considered a major health burden worldwide, especially when they result in sepsis and …

Genotypic Characterization of Clinical Klebsiella spp. Isolates Collected From Patients With Suspected Community-Onset Sepsis, Sweden

P Saxenborn, J Baxter, A Tilevik, M Fagerlind… - Frontiers in …, 2021 - frontiersin.org
Klebsiella is a genus of Gram-negative bacteria known to be opportunistic pathogens that
may cause a variety of infections in humans. Highly drug-resistant Klebsiella species …

Sepsityper® Kit versus In-House Method in Rapid Identification of Bacteria from Positive Blood Cultures by MALDI-TOF Mass Spectrometry

G Perše, I Samošćanec, Z Bošnjak, A Budimir, T Kuliš… - Life, 2022 - mdpi.com
In order to further accelerate pathogen identification from positive blood cultures (BC),
various sample preparation protocols to identify bacteria with MALDI-TOF MS directly from …

Benchmarking of two bioinformatic workflows for the analysis of whole-genome sequenced Staphylococcus aureus collected from patients with suspected sepsis

MI Shemirani, D Tilevik, A Tilevik, S Jurcevic… - BMC Infectious …, 2023 - Springer
Background The rapidly growing area of sequencing technologies, and more specifically
bacterial whole-genome sequencing, could offer applications in clinical microbiology …

An in-house centrifugation and membrane filtration technique for identifying microorganisms from positive blood culture bottles with high identification rates using …

S Tsuchida, S Murata, A Miyabe, M Satoh… - Journal of Infection and …, 2020 - Elsevier
Matrix-assisted laser desorption ionization–time-of-flight mass spectrometry (MALDI-TOF
MS) is one of the most promising technologies for the identification of microbial pathogens …

Genotypic characterization of Enterococci isolates from patients suspected with community-onset sepsis, Sweden

TT Trinh - 2024 - diva-portal.org
Sepsis, a life-threatening condition with alarmingly high mortality rates, demands the
development of improved diagnostic methods to better understand and manage the disease …