Significant progress has been made recently in unravelling the embryonic events leading to
pituitary morphogenesis, both in vivo and in vitro. This includes dissection of the molecular …

Owing to its complex structure and highly diverse cell populations, the study of hypothalamic
development has historically lagged behind that of other brain regions. However, in recent …

The neuroendocrine hypothalamus is composed of the tuberal and anterodorsal
hypothalamus, together with the median eminence/neurohypophysis. It centrally governs …

Background Activated microglial cells release an excess of inflammatory mediators after an
ischemic stroke. We reported previously that scutellarin effectively suppressed the …

Significant progress has been made recently in unravelling the embryonic events leading to
pituitary morphogenesis, both in vivo and in vitro. This includes dissection of the molecular …

The medial hypothalamus is composed of nuclei of the tuberal hypothalamus, the
paraventricular nucleus of the anterior hypothalamus, and the neurohypophysis. Its …

Holoprosencephaly is a pathology of forebrain development characterized by high
phenotypic heterogeneity. The disease presents with various clinical manifestations at the …

The neural crest (NC), discovered by Wilhelm His 150 years ago, gives rise to a multipotent
migratory embryonic cell population that generates a remarkably diverse and important …

The adult hypothalamus regulates many physiological functions and homeostatic loops,
including growth, feeding and reproduction. In mammals, the hypothalamus derives from the …

Combined pituitary hormone deficiency (CPHD) is not a rare disorder, with a frequency of
approximately 1 case per 4,000 live births. However, in most cases, a genetic diagnosis is …