[HTML][HTML] Neutrophil elastase inhibitors and chronic kidney disease

E Bronze-da-Rocha, A Santos-Silva - International journal of …, 2018 - ncbi.nlm.nih.gov
End-stage renal disease (ESRD), the last stage of chronic kidney disease (CKD), is
characterized by chronic inflammation and oxidative stress. Neutrophils are the front line …

Red blood cell abnormalities and the pathogenesis of anemia in end‐stage renal disease

HT Georgatzakou, MH Antonelou… - PROTEOMICS …, 2016 - Wiley Online Library
Anemia is the most common hematologic complication in end‐stage renal disease (ESRD).
It is ascribed to decreased erythropoietin production, shortened red blood cell (RBC) …

Uric acid variation among regular blood donors is indicative of red blood cell susceptibility to storage lesion markers: a new hypothesis tested

VL Tzounakas, HT Georgatzakou, AG Kriebardis… - …, 2015 - Wiley Online Library
BACKGROUND Oxidative stress orchestrates a significant part of the red blood cell (RBC)
storage lesion. Considering the tremendous interdonor variability observed in the …

Changes in FGF-23, neutrophil/platelet activation markers, and angiogenin in advanced chronic kidney disease and their effect on arterial stiffness

HM Choi, YE Kwon, S Kim, DJ Oh - Kidney and Blood Pressure …, 2019 - karger.com
Aims: The aims of this study were to measure changes in fibroblast growth factor 23 (FGF-
23), neutrophil (elastase, lactoferrin)/platelet activation marker (mean platelet volume-to …

Pregnancy outcomes among renal transplant recipients and patients with end-stage renal disease on dialysis

S Saliem, V Patenaude, HA Abenhaim - Journal of Perinatal …, 2016 - degruyter.com
Aim: The purpose of our study is to compare pregnancy outcomes between women with a
functioning renal transplant and women with end-stage renal disease (ESRD). Methods: We …

The multi-faced extracellular vesicles in the plasma of chronic kidney disease patients

HT Georgatzakou, EG Pavlou… - Frontiers in Cell and …, 2020 - frontiersin.org
Extracellular vesicles (EVs) are membrane-enclosed nanoparticles released by most cells in
body fluids and extracellular matrix. They function as signal transducers in intercellular …

Short-term effects of hemodiafiltration versus conventional hemodialysis on erythrocyte performance

HT Georgatzakou, VL Tzounakas… - Canadian journal of …, 2018 - cdnsciencepub.com
Hemodiafiltration (HDF) is a renal replacement therapy that is based on the principles of
diffusion and convection for the elimination of uremic toxins. A significant and increasing …

Pathophysiological aspects of red blood cells in end‐stage renal disease patients resistant to recombinant human erythropoietin therapy

HT Georgatzakou, VL Tzounakas… - European journal of …, 2017 - Wiley Online Library
Objective Modified, bioreactive red blood cells (RBC s) and RBC‐derived microvesicles
(MVs) likely contribute to the hematological and cardiovascular complications in end‐stage …

Determinants of thromboxane biosynthesis in patients with moderate to severe chronic kidney disease

N Vazzana, F Santilli, S Lattanzio, M Liani… - European Journal of …, 2016 - Elsevier
Background Mechanisms of accelerated atherothrombosis in patients with chronic kidney
disease (CKD) are only partly characterized. The aims of this study were to evaluate the …

Urine proteomics reveals sex-specific response to total pancreatectomy with islet autotransplantation

TB Bennike, K Templeton, K Fujimura, MD Bellin… - Pancreas, 2022 - journals.lww.com
Objectives Total pancreatectomy with islet autotransplantation (TPIAT) is a surgical option
for refractory chronic pancreatitis-related pain. Despite the known clinical implications of …