Glomerular hyperfiltration

M Cortinovis, N Perico, P Ruggenenti… - Nature reviews …, 2022 - nature.com
Circulating blood is filtered across the glomerular barrier to form an ultrafiltrate of plasma in
the Bowman's space. The volume of glomerular filtration adjusted by time is defined as the …

Impact of gender and gender disparities in patients with kidney disease

A Brar, M Markell - Current opinion in nephrology and …, 2019 - journals.lww.com
Recommendations for medical management of CKD patients are currently made in a gender-
blind manner, despite the fact that women have differing underlying physiology. Addressing …

A multinational cohort study uncovered sex differences in excess mortality after kidney transplant

AJ Vinson, X Zhang, M Dahhou, C Süsal, B Döhler… - Kidney International, 2023 - Elsevier
Worldwide and at all ages, males have a higher mortality risk than females. This mortality
bias should be preserved in kidney transplant recipients unless there are sex differences in …

Age-dependent sex differences in graft loss after kidney transplantation

AJ Vinson, X Zhang, M Dahhou, C Süsal… - …, 2022 - journals.lww.com
Background. Sex differences in kidney graft loss rates were reported in the United States.
Whether these differences are present in other countries is unknown. Methods. We …

Why do we keep ignoring sex in kidney disease?

M Jankowska, MJ Soler, KI Stevens… - Clinical Kidney …, 2023 - academic.oup.com
Throughout the history of nephrology, little attention has been paid to the sex and gender
differences in kidney disease. This lack of awareness prevents optimal diagnosis and …

[HTML][HTML] Sex as a biological variable: Mechanistic insights and clinical relevance in solid organ transplantation

Y Xiao, A Schroeter, F Martin, T Matsunaga… - American Journal of …, 2023 - Elsevier
Biological sex affects immunity broadly with recognized effects on incidence and severity of
autoimmune diseases, infections and malignancies. Consequences of sex on alloimmunity …

[HTML][HTML] Deceased donor characteristics and kidney transplant outcomes

A Sharif - Transplant International, 2022 - frontierspartnerships.org
Kidney transplantation is the therapy of choice for people living with kidney failure who are
suitable for surgery. However, the disparity between supply versus demand for organs …

The effect of sex inequality on solid organ transplantation: A systematic review and meta-analysis

S Tejada, R Martinez-Reviejo, TA Nogueira… - European Journal of …, 2023 - Elsevier
Background Sex disparities are related to biological differences, which may have significant
impact on patient and allograft outcomes. The aim was to investigate the impact of sex on …

[HTML][HTML] Rethinking incompatibility in kidney transplantation

KR Jackson, DL Segev - American Journal of Transplantation, 2022 - Elsevier
Donor/recipient incompatibility in kidney transplantation classically refers to ABO/HLA-
incompatibility. Kidney paired donation (KPD) was historically established to circumvent …

Obesity in kidney transplantation: impact on transplant candidates, recipients, and donors

D Glicklich, MR Mustafa - Cardiology in Review, 2019 - journals.lww.com
Obesity is now common among children and adults who are kidney transplant candidates
and recipients. It is associated with an increased risk of cardiovascular disease and kidney …