We now know that cancer is many different diseases, with great variation even within a
single histological subtype. With the current emphasis on developing personalized …

Bisphenol A (BPA) is a non-persistent anthropic and environmentally ubiquitous compound
widely employed and detected in many consumer products and food items; thus, human …

Background The early life environment experienced by an individual in utero and during the
neonatal period is a major factor in shaping later life disease risk-including susceptibility to …

Sexual dimorphism is a key factor to consider in the ageing process given the impact that it
has on life expectancy. The oxidative-inflammatory theory of ageing states that the ageing …

Autoimmune diseases are characterized by circulating antibodies and immune complexes
directed against self-tissues that result in both systemic and organ-specific inflammation and …

The convergence of tissue engineering and patient-specific stem cell biology has enabled
the engineering of in vitro tissue models that allow the study of patient-tailored treatment …

Mitochondria are unique organelles present in almost all cell types. They are involved not
only in the supply of energy to the host cell, but also in multiple biochemical and biological …

Genetic, developmental, biochemical, and environmental variables interact intricately to
produce sex differences. The significance of sex differences in cancer susceptibility is being …

The nervous system is a target and a source of steroids. Neuroactive steroids are steroids
that target neurons and glial cells. They include hormonal steroids originated in the …

Mitochondrial damage is a critical contributor to stroke‐induced injury, and mitochondrial
quality control (MQC) is the cornerstone of restoring mitochondrial homeostasis and plays …