Theranostic nanoparticles with disease-specific administration strategies

P Zhang, Y Li, W Tang, J Zhao, L Jing, KJ McHugh - Nano Today, 2022 - Elsevier
Recent advances in the synthesis of nanomaterials with diagnostic and therapeutic
capabilities have been rapidly reshaping the landscape of precision medicine. Impressive …

[PDF][PDF] Gadolinium (III) chelates as MRI contrast agents: structure, dynamics, and applications

P Caravan, JJ Ellison, TJ McMurry… - Chemical …, 1999 - s.mriquestions.com
Gadolinium, an obscure lanthanide element buried in the middle of the periodic table, has in
the course of a decade become commonplace in medical diagnostics. Like platinum in …

Molecular imaging

R Weissleder, U Mahmood - Radiology, 2001 - pubs.rsna.org
The term molecular imaging can be broadly defined as the in vivo characterization and
measurement of biologic processes at the cellular and molecular level. In contradistinction to …

Macromolecules, dendrimers, and nanomaterials in magnetic resonance imaging: the interplay between size, function, and pharmacokinetics

AJL Villaraza, A Bumb, MW Brechbiel - Chemical reviews, 2010 - ACS Publications
Magnetism in medicine has had a long and interesting history. In the 10th century AD,
Egyptian physician and philosopher Avicenna prescribed a grain of magnetite dissolved in …

Hypersensitive MR angiography based on interlocking stratagem for diagnosis of cardiac-cerebral vascular diseases

P Zhang, J Cheng, Y Lu, N Zhang, X Wu, H Lin… - Nature …, 2023 - nature.com
Magnetic resonance (MR) angiography is one of the main diagnostic approaches for cardiac-
cerebral vascular diseases. Nevertheless, the non-contrast-enhanced MR angiography …

Poly(l-lysine)-g-Poly(ethylene glycol) Layers on Metal Oxide Surfaces:  Attachment Mechanism and Effects of Polymer Architecture on Resistance to Protein …

GL Kenausis, J Vörös, DL Elbert, N Huang… - The Journal of …, 2000 - ACS Publications
The generation of surfaces and interfaces that are able to withstand protein adsorption is a
major challenge in the design of blood-contacting materials for both medical implants and …

Non-antigenic branched polymer conjugates

A Martinez, RB Greenwald - US Patent 5,643,575, 1997 - Google Patents
BACKGROUND OF THE INVENTION 1. Field of the Invention The present invention relates
to branched polymers which are useful in extending the in vivo circulating life of bio logically …

Nano-sized MRI contrast agents with dendrimer cores

H Kobayashi, MW Brechbiel - Advanced drug delivery reviews, 2005 - Elsevier
Gadolinium-based MRI contrast agents (CAs) can be effective at a∼ 100-fold lower
concentration of Gadolinium ions in comparison to the concentration of Iodine atoms …

Water-soluble non-antigenic polymer linkable to biologically active material

RB Greenwald, AJ Martinez - US Patent 6,113,906, 2000 - Google Patents
Branched, substantially non-antigenic polymers are disclosed. Conjugates prepared with
the polymers and biologically active molecules such as proteins and peptides demonstrate …

Non-antigenic branched polymer conjugates

RB Greenwald, AJ Martinez - US Patent 5,919,455, 1999 - Google Patents
Branched, substantially non-antigenic polymers are disclosed. Conjugates prepared with
the polymers and biologically active molecules such as proteins and peptides demonstrate …