IMI–Report on experimental models of emmetropization and myopia

D Troilo, EL Smith, DL Nickla, R Ashby… - … & visual science, 2019 - iovs.arvojournals.org
The results of many studies in a variety of species have significantly advanced our
understanding of the role of visual experience and the mechanisms of postnatal eye growth …

Scleral structure and biomechanics

C Boote, IA Sigal, R Grytz, Y Hua, TD Nguyen… - Progress in retinal and …, 2020 - Elsevier
As the eye's main load-bearing connective tissue, the sclera is centrally important to vision.
In addition to cooperatively maintaining refractive status with the cornea, the sclera must …

The dynamic sclera: extracellular matrix remodeling in normal ocular growth and myopia development

AR Harper, JA Summers - Experimental eye research, 2015 - Elsevier
Myopia is a common ocular condition, characterized by excessive elongation of the ocular
globe. The prevalence of myopia continues to increase, particularly among highly educated …

Light levels, refractive development, and myopia–a speculative review

TT Norton, JT Siegwart Jr - Experimental eye research, 2013 - Elsevier
Recent epidemiological evidence in children indicates that time spent outdoors is protective
against myopia. Studies in animal models (chick, macaque, tree shrew) have found that light …

[HTML][HTML] Long-wavelength (red) light produces hyperopia in juvenile and adolescent tree shrews

TJ Gawne, AH Ward, TT Norton - Vision Research, 2017 - Elsevier
In infant tree shrews, exposure to narrow-band long-wavelength (red) light, that stimulates
long-wavelength sensitive cones almost exclusively, slows axial elongation and produces …

[HTML][HTML] Near infrared (NIR) light therapy of eye diseases: a review

Q Zhu, S Xiao, Z Hua, D Yang, M Hu… - … journal of medical …, 2021 - ncbi.nlm.nih.gov
Near infrared (NIR) light therapy, or photobiomodulation therapy (PBMT), has gained
persistent worldwide attention in recent years as a new novel scientific approach for …

The wavelength composition and temporal modulation of ambient lighting strongly affect refractive development in young tree shrews

TJ Gawne, JT Siegwart Jr, AH Ward… - Experimental eye research, 2017 - Elsevier
Shortly after birth, the eyes of most animals (including humans) are hyperopic because the
short axial length places the retina in front of the focal plane. During postnatal development …

[HTML][HTML] Pharmacotherapeutic candidates for myopia: a review

WY Wang, C Chen, J Chang, L Chien, YF Shih… - Biomedicine & …, 2021 - Elsevier
This review provides insights into the mechanism underlying the pathogenesis of myopia
and potential targets for clinical intervention. Although the etiology of myopia involves both …

The role of luminance and chromatic cues in emmetropisation

FJ Rucker - Ophthalmic and Physiological Optics, 2013 - Wiley Online Library
Purpose At birth most, but not all eyes, are hyperopic. Over the course of the first few years of
life the refraction gradually becomes close to zero through a process called …

[HTML][HTML] Functional integration of eye tissues and refractive eye development: Mechanisms and pathways

JA Summers, F Schaeffel, S Marcos, H Wu… - Experimental Eye …, 2021 - Elsevier
Refractive eye development is a tightly coordinated developmental process. The general
layout of the eye and its various components are established during embryonic …