Diagnosis and management of functional neurological disorder

S Aybek, DL Perez - bmj, 2022 - bmj.com
Functional neurological disorder (FND), previously regarded as a diagnosis of exclusion, is
now a rule-in diagnosis with available treatments. This represents a major step toward …

Psychogenic nonepileptic seizures: review and update

M Reuber, CE Elger - Epilepsy & Behavior, 2003 - Elsevier
The population incidence of psychogenic nonepileptic seizures (PNES) may be only 4% that
of epilepsy, but many patients with PNES have a tendency to seek medical attention, and …

Distribution of partial seizures during the sleep–wake cycle: differences by seizure onset site

ST Herman, TS Walczak, CW Bazil - Neurology, 2001 - AAN Enterprises
Objective: To evaluate the effects of sleep on partial seizures arising from various brain
regions. Methods: The authors prospectively studied 133 patients with localization-related …

Glia-neuron interactions underlie state transitions to generalized seizures

C Diaz Verdugo, S Myren-Svelstad, E Aydin… - Nature …, 2019 - nature.com
Brain activity and connectivity alter drastically during epileptic seizures. The brain networks
shift from a balanced resting state to a hyperactive and hypersynchronous state. It is …

Chronobiology, drug delivery, and chronotherapeutics

MH Smolensky, NA Peppas - Advanced drug delivery reviews, 2007 - Elsevier
Biological processes and functions are organized in space, as a physical anatomy, and time,
as a biological time structure. The latter is expressed by short-, intermediate-, and long …

Why are seizures rare in rapid eye movement sleep? Review of the frequency of seizures in different sleep stages

M Ng, M Pavlova - Epilepsy research and treatment, 2013 - Wiley Online Library
Since the formal characterization of sleep stages, there have been reports that seizures may
preferentially occur in certain phases of sleep. Through ascending cholinergic connections …

Does the primary literature provide support for clinical signs used to distinguish psychogenic nonepileptic seizures from epileptic seizures?

A Avbersek, S Sisodiya - Journal of Neurology, Neurosurgery & …, 2010 - jnnp.bmj.com
Psychogenic non-epileptic seizures (PNES) represent a diagnostic challenge. When trying
to distinguish between PNES and epileptic seizures (ES), clinicians rely on the presence or …

Psychogenic nonepileptic seizures: answers and questions

M Reuber - Epilepsy & behavior, 2008 - Elsevier
Psychogenic nonepileptic seizures (PNES) superficially resemble epileptic seizures, but are
not associated with ictal electrical discharges in the brain. PNES constitute one of the most …

Epilepsy and sleep disturbance

CW Bazil - Epilepsy & Behavior, 2003 - Elsevier
Sleep disturbance is common in epilepsy, the nature of sleep disturbances in epilepsy is
diverse, and the etiologies are complex. Evidence suggests that having epilepsy and the …

A review of diagnostic techniques in the differential diagnosis of epileptic and nonepileptic seizures

DE Cragar, DTR Berry, TA Fakhoury, JE Cibula… - Neuropsychology …, 2002 - Springer
The diagnosis of psychogenic nonepileptic seizures (PNES) is complex. Long-term
electroencephalogram monitoring with video recording (video EEG) is the most common …