Cerebral complications of snakebite envenoming: case studies

YK Huang, YC Chen, CC Liu, HC Cheng, AT Tu… - Toxins, 2022 - mdpi.com
There are an estimated 5.4 million snakebite cases every year. People with snakebite
envenoming suffer from severe complications, or even death. Although some review articles …

[HTML][HTML] Snake venom vascular endothelial growth factors (svVEGFs): Unravelling their molecular structure, functions, and research potential

IG Ferreira, MB Pucca, IS de Oliveira, FA Cerni… - Cytokine & Growth …, 2021 - Elsevier
Vascular endothelial growth factor (VEGF) is a key regulator of angiogenesis, a
physiological process characterized by the formation of new vessels from a preexisting …

[HTML][HTML] Comparative characterization of Viperidae snake venoms from Perú reveals two compositional patterns of phospholipase A2 expression

B Lomonte, C Díaz, F Chaves, J Fernández, M Ruiz… - Toxicon: X, 2020 - Elsevier
Snake species within the Bothrops complex (sensu lato) are of medical relevance in Latin
America, but knowledge on their venom characteristics is limited, or even unavailable, for …

Clinical and Evolutionary Implications of Dynamic Coagulotoxicity Divergences in Bothrops (Lancehead Pit Viper) Venoms

LA Bourke, CN Zdenek, AM Tanaka-Azevedo… - Toxins, 2022 - mdpi.com
Despite coagulotoxicity being a primary weapon for prey capture by Bothrops species
(lancehead pit vipers) and coagulopathy being a major lethal clinical effect, a genus-wide …

Bothrops atrox venom: Biochemical properties and cellular phenotypes of three highly toxic classes of toxins

L Lopes-de-Souza, F Costal-Oliveira… - … et Biophysica Acta (BBA …, 2023 - Elsevier
Snake venoms have a complex mixture of compounds that are conserved across species
and act synergistically, triggering severe local and systemic effects. Identification of the toxin …

Danger in the canopy. Comparative proteomics and bioactivities of the venoms of the South American palm pit viper Bothrops bilineatus subspecies bilineatus and …

L Sanz, S Quesada-Bernat, A Pérez… - Journal of proteome …, 2020 - ACS Publications
We report a structural and functional proteomics characterization of venoms of the two
subspecies (Bothrops bilineatus bilineatus and B. b. smaragdinus) of the South American …

[HTML][HTML] Production of a murine mAb against Bothrops alternatus and B. neuwiedi snake venoms and its use to isolate a thrombin-like serine protease fraction

AA Belo, DLN de Souza, MN de Melo-Braga… - International Journal of …, 2022 - Elsevier
Accidents with snakes from the genus Bothrops represent~ 90% of all snakebites in Brazil.
Monoclonal antibodies (mAbs) targeting venom components can be important assets for …

[HTML][HTML] Proteomic and toxinological characterization of Peruvian pitviper Bothrops brazili (“jergón shushupe”), venom

CR Rodrigues, DAM Molina, TCS de Assis, C Liberato… - Toxicon, 2020 - Elsevier
Bothrops brazili is a pitviper from Amazonian region, responsible for many accidents in Peru.
Despite its relevance, its venom has not been extensively characterized. In the present work …

[PDF][PDF] Métodos alternativos para determinação da potência de veneno e antiveneno botrópico: aplicações e perspectivas para o controle da qualidade

RNC Nundes, HP De Araújo, GG Alves… - Vigilância Sanitária em …, 2022 - redalyc.org
Introdução: Acidentes com animais peçonhentos são classificados como doenças tropicais
negligenciadas e são atualmente a mais frequente causa de intoxicação em humanos no …

Bothrops bilineatus: An Arboreal Pitviper in the Amazon and Atlantic Forest

PS Bernarde, MB Pucca, A Mota-da-Silva… - Frontiers in …, 2021 - frontiersin.org
The two-striped forest-pitviper (Bothrops bilineatus) is an arboreal snake that is currently
represented by two subspecies (B. b. bilineatus and B. b. smaragdinus) that comprise a …