Skeletal muscles, being one of the most abundant tissues in the body, are involved in many
vital processes, such as locomotion, posture maintenance, respiration, glucose …

Lithium is most well-known for its mood-stabilizing effects in the treatment of bipolar
disorder. Due to its narrow therapeutic window (0.5-1.2 mM serum concentration), there is a …

Cellular responses to stimuli underpin discoveries in drug development, synthetic biology,
and general life sciences. We introduce a library comprising 6144 synthetic promoters, each …

Inhibiting glycogen synthase kinase 3 (GSK3) improves muscle function, metabolism, and
bone health in many diseases and conditions; however, whether GSK3 should be targeted …

Skeletal muscle is capable of changing its structural parameters, metabolic rate and
functional characteristics within a wide range when adapting to various loading regimens …

Sarco (endo) plasmic reticulum Ca 2+-ATPase (SERCA) uncoupling in skeletal muscle and
mitochondrial uncoupling via uncoupling protein 1 (UCP1) in brown/beige adipose tissue …

The trace element lithium exerts a versatile bioactivity in humans, to some extend
overlapping with in vivo findings in the model organism Drosophila melanogaster. A …

There is evidence that chronic fatigue spectrum disorders (CFAS-Ds), including myalgic
encephalomyelitis (ME), chronic fatigue syndrome (CFS), and chronic fatigue with …

Inflammation-mediated skeletal muscle wasting occurs in patients with sepsis and cancer
cachexia. Both conditions severely affect patient morbidity and mortality. Lithium chloride …

Muscle wasting is a major pathological feature observed in Duchenne muscular dystrophy
(DMD) and is the result of the concerted effects of inflammation, oxidative stress and cell …