Inflammation clearly occurs in pathologically vulnerable regions of the Alzheimer's disease
(AD) brain, and it does so with the full complexity of local peripheral inflammatory responses …

Alzheimer's disease (AD) is the most prevalent form of neurodegenerative disease, currently
affecting over 5 million Americans with projections expected to rise as the population ages …

Neuroinflammation is a common feature in neurodegenerative diseases, modulated by the
Alzheimer's disease risk factor, apolipoprotein E (APOE). In the brain, apoE protein is …

The most prevalent genetic risk factor for Alzheimer's disease (AD) is Apolipoprotein E
(ApoE), a gene located on chromosome 19 that encodes three alleles (e2, e3, and e4) that …

Alzheimer's disease (AD) is the most common form of dementia, with progressive cognitive
deficits being the primary symptom. AD is neuropathologically characterized by amyloid and …

The ϵ4 allele of the Apolipoprotein E (APOE) gene is the strongest genetic risk factor for late‐
onset Alzheimer's disease (AD), and affects clinical outcomes of chronic and acute brain …

Despite more than a century of research, the aetiology of sporadic Alzheimer's disease (AD)
remains unclear and finding disease modifying treatments for AD presents one of the …

A common feature of Alzheimer's disease (AD) pathology is the abundance of reactive
astrocytes and activated microglia in close proximity to neuritic plaques containing amyloid …

Apolipoprotein E plays an important role in recovery from acute brain injury and risk of
developing Alzheimer's disease. We demonstrate that biologically relevant concentrations of …

In the past five years, a series of large-scale genetic studies have revealed novel risk factors
for Alzheimer's disease (AD). Analyses of these risk factors have focused attention upon the …