The benefits gained by young animals engaging in play fighting have been a subject of
conjecture for over a hundred years. Progress in understanding the behavioral development …

Background Synthetic cannabinoids (SC) are a heterogeneous group of compounds
developed to probe the endogenous cannabinoid system or as potential therapeutics …

In the young of many mammalian species, including humans, a vigorous and highly
rewarding social activity is abundantly expressed, known as social play behaviour. Social …

A groundbreaking study into the formative role of play in our lives Sergio and Vivien Pellis
have synthesized three decades of empirical research to create a remarkable work …

Research across species highlights the critical role of the amygdala in fear conditioning.
However, fear conditioning, involving direct aversive experience, is only one means by …

This article reviews neuroimaging, neurocognitive, and preclinical findings on the effects of
cannabis on the adolescent brain. Marijuana is the second most widely used intoxicant in …

Studies using animal models of adolescent exposure to alcohol, nicotine, cannabinoids, and
the stimulants cocaine, 3, 4-methylenedioxymethampethamine and methamphetamine have …

Memory problems are frequently associated with cannabis use, in both the short-and long-
term. To date, reviews on the long-term cognitive sequelae of cannabis use have examined …

Adolescence and puberty are highly important periods for postnatal brain maturation. During
adolescence, drastic changes of neuronal architecture and function occur that concomitantly …

Human epidemiological studies have provided compelling evidence that the risk of
developing schizophrenia is significantly enhanced following prenatal and/or perinatal …