Controls of hair follicle cycling

KS Stenn, R Paus - Physiological reviews, 2001 - journals.physiology.org
Nearly 50 years ago, Chase published a review of hair cycling in which he detailed hair
growth in the mouse and integrated hair biology with the biology of his day. In this review we …

[HTML][HTML] A comprehensive guide for the accurate classification of murine hair follicles in distinct hair cycle stages

S Müller-Röver, K Foitzik, R Paus, B Handjiski… - Journal of investigative …, 2001 - Elsevier
Numerous strains of mice with defined mutations display pronounced abnormalities of hair
follicle cycling, even in the absence of overt alterations of the skin and hair phenotype; …

Macrophages induce AKT/β-catenin-dependent Lgr5+ stem cell activation and hair follicle regeneration through TNF

X Wang, H Chen, R Tian, Y Zhang… - Nature …, 2017 - nature.com
Skin stem cells can regenerate epidermal appendages; however, hair follicles (HF) lost as a
result of injury are barely regenerated. Here we show that macrophages in wounds activate …

Corticotropin releasing hormone and proopiomelanocortin involvement in the cutaneous response to stress

A Slominski, J Wortsman, T Luger… - Physiological …, 2000 - journals.physiology.org
The skin is a known target organ for the proopiomelanocortin (POMC)-derived
neuropeptides α-melanocyte stimulating hormone (α-MSH), β-endorphin, and ACTH and …

Human hair follicles display a functional equivalent of the hypothalamic‐pituitary‐adrenal (HPA) axis and synthesize cortisol

N Ito, T Ito, A Kromminga, A Bettermann… - The FASEB …, 2005 - Wiley Online Library
The skin and its major appendages are prominent target organs and potent sources of key
players along the classical hypothalamic‐pituitary axis, such as corticotropin releasing …

Analysis of apoptosis during hair follicle regression (catagen)

G Lindner, VA Botchkarev, NV Botchkareva… - The American journal …, 1997 - ncbi.nlm.nih.gov
Keratinocyte apoptosis is a central element in the regulation of hair follicle regression
(catagen), yet the exact location and the control of follicular keratinocyte apoptosis remain …

Natural tyrosinase enzyme inhibitors: A path from melanin to melanoma and its reported pharmacological activities

R Logesh, SR Prasad, S Chipurupalli… - … et Biophysica Acta (BBA …, 2023 - Elsevier
The skin containing melanin pigment acts as a protective barrier and counteracts the UVR
and other environmental stressors to maintain or restore disrupted cutaneous homeostasis …

Cathepsin L deficiency as molecular defect of furless: hyperproliferation of keratinocytes and pertubation of hair follicle cycling

W Roth, JAN Deussing, VA Botchkarev… - The FASEB …, 2000 - Wiley Online Library
Lysosomal cysteine proteinases of the papain family are involved in lysosomal bulk
proteolysis, major histocompatibility complex class II mediated antigen presentation …

Apoptosis as a mechanism of keratinocyte death in toxic epidermal necrolysis

C Paul, P Wolkenstein, H Adle… - British Journal of …, 1996 - academic.oup.com
Toxic epidermal necrolysis (TEN) and Stevens‐Johnson syndrome (SJS) are life‐
threatening diseases characterized by extensive epidermal destruction. The aim of our study …

Molecular biology of hair morphogenesis: development and cycling

VA Botchkarev, R Paus - Journal of Experimental Zoology Part …, 2003 - Wiley Online Library
In mammals, hair follicles produce hairs that fulfill a number of functions including
thermoregulation, collecting sensory information, protection against environmental trauma …