Parkinson's Disease‐Induced Zebrafish Models: Focussing on Oxidative Stress Implications and Sleep Processes

MA Robea, IM Balmus, A Ciobica… - Oxidative Medicine …, 2020 - Wiley Online Library
The complex yet not fully understood pathophysiology of Parkinson's disease includes an
important molecular component consisting of oxidative status changes, thus leading to …

Brain microstructural alterations of depression in Parkinson's disease: A systematic review of diffusion tensor imaging studies

MA Salehi, S Mohammadi, M Gouravani… - Human Brain …, 2022 - Wiley Online Library
Depression, a leading cause of disability worldwide, is also the most prevalent psychiatric
problem among Parkinson disease patients. Both depression and Parkinson disease are …

Convergent patterns of structural brain changes in rapid eye movement sleep behavior disorder and Parkinson's disease on behalf of the German rapid eye …

F Holtbernd, S Romanzetti, WH Oertel, S Knake… - Sleep, 2021 - academic.oup.com
Abstract Study Objectives Rapid eye movement sleep behavior disorder (RBD) is
considered a prodromal state of Parkinson's disease (PD). We aimed to characterize …

Assessing white matter pathology in early-stage Parkinson disease using diffusion MRI: a systematic review

M Bergamino, EG Keeling, VR Mishra… - Frontiers in …, 2020 - frontiersin.org
Structural brain white matter (WM) changes such as axonal caliber, density, myelination, and
orientation, along with WM-dependent structural connectivity, may be impacted early in …

Impaired white matter microstructure associated with severe depressive symptoms in patients with PD

Q Shen, Y Liu, J Guo, H Zhang, Y Xiang, H Liao… - Brain Imaging and …, 2022 - Springer
Depression is a common occurrence in patients with Parkinson's disease (PD); however, its
pathophysiology is still unclear. This study assessed the association between the integrity of …

Cingulum and Uncinate fasciculus microstructural abnormalities in Parkinson's disease: a systematic review of diffusion tensor imaging studies

F Rashidi, MH Khanmirzaei, F Hosseinzadeh… - Biology, 2023 - mdpi.com
Simple Summary This article reviews the use of diffusion tensor imaging (DTI) to evaluate
changes in white matter microstructure within two specific fiber tracts in Parkinson's disease …

Sleep differentially and profoundly impairs recall memory in a patient with fornix damage

N Matorina, J Tseng, N Ladyka-Wojcik… - Journal of Cognitive …, 2023 - direct.mit.edu
In March 2020, CT, a kind, bright, and friendly young woman underwent surgery for a
midline tumor involving her septum pellucidum and extending down into her fornices …

Association of olfaction dysfunction with brain microstructure in prodromal Parkinson disease

H Sanjari Moghaddam, M Dolatshahi, E Salardini… - Neurological …, 2019 - Springer
Objective Although olfaction dysfunction is now considered as an established clinical marker
of prodromal Parkinson disease (PD), little is known about the neural underpinnings of …

Abnormal white matter microstructures in Parkinson's disease and comorbid depression: a whole-brain diffusion tensor imaging study

Z Li, W Liu, C Xiao, X Wang, X Zhang, M Yu, X Hu… - Neuroscience …, 2020 - Elsevier
Objective Depressive symptoms are the most common non-motor symptom accompanying
Parkinson's disease (PD); however, the neural basis of depression in PD remains unclear …

Changes in day/night activity in the 6-OHDA-induced experimental model of Parkinson's disease: Exploring prodromal biomarkers

C Requejo, K López-de-Ipiña, JÁ Ruiz-Ortega… - Frontiers in …, 2020 - frontiersin.org
The search for experimental models mimicking an early stage of Parkinson's disease (PD)
before motor manifestations is fundamental in order to explore early signs and get a better …