A scientific evaluation was made of functionalspects of developmental toxicity of
polychlorinated biphenyls (PCBs), polychlorinated dibenzo-p-dioxins (PCDDs) and …

Iodothyronine deiodinases (D1, D2, and D3) comprise a family of selenoproteins that are
involved in the conversion of thyroxine (T4) to active triiodothyronine (T3), and also the …

Stress blocks hippocampal primed-burst potentiation, a low threshold form of long-term
potentiation, thereby suggesting that stress should also impair hippocampal-dependent …

The effects of chronic and acute corticosterone (CORT) administration were investigated on
hippocampal long‐term potentiation (LTP) in the dentate gyrus granule cell layer of the rat …

Abstract Type 3 iodothyronine deiodinase (D3) is a selenoenzyme that inactivates thyroid
hormone. It is necessary for T3 homeostasis in the central nervous system. D3 activity has …

Ghrelin, an orexigenic hormone, is mainly produced by the stomach and released into the
circulation. Ghrelin receptors (growth hormone secretagogue receptors) are expressed …

Thyroid hormone deficiency has long been considered to affect profoundly such cognitive
functions as learning and memory, which are known to depend on the structural integrity of …

Thyroid hormones are critical for the development and maturation of the central nervous
system. Although somatic and neurological effects are well documented following severe …

Hyperthyroidism has been identified as a risk factor for cognitive disorders. The
hippocampus is a key brain region associated with cognitive function, among which …

Pregnant ICR mice were subcutaneously injected with 0, 5, or 3× 3 mg Hg/kg of
methylmercury (MeHg) on days 12, 13, and 14 (G12–14) of gestation and were sacrificed on …