Chemical strategies to engineer hydrogels for cell culture

J Lou, DJ Mooney - Nature Reviews Chemistry, 2022 - nature.com
Two-dimensional and three-dimensional cell culture systems are widely used for biological
studies, and are the basis of the organoid, tissue engineering and organ-on-chip research …

Engineered hydrogels for mechanobiology

U Blache, EM Ford, B Ha, L Rijns… - Nature Reviews …, 2022 - nature.com
Cells' local mechanical environment can be as important in guiding cellular responses as
many well-characterized biochemical cues. Hydrogels that mimic the native extracellular …

[HTML][HTML] Smart/stimuli-responsive hydrogels: Cutting-edge platforms for tissue engineering and other biomedical applications

HM El-Husseiny, EA Mady, L Hamabe, A Abugomaa… - Materials Today Bio, 2022 - Elsevier
Recently, biomedicine and tissue regeneration have emerged as great advances that
impacted the spectrum of healthcare. This left the door open for further improvement of their …

Synthetic dynamic hydrogels promote degradation-independent in vitro organogenesis

A Chrisnandy, D Blondel, S Rezakhani, N Broguiere… - Nature Materials, 2022 - nature.com
Epithelial organoids are most efficiently grown from mouse-tumour-derived, reconstituted
extracellular matrix hydrogels, whose poorly defined composition, batch-to-batch variability …

Highly compressible glass-like supramolecular polymer networks

Z Huang, X Chen, SJK O'Neill, G Wu, DJ Whitaker… - Nature materials, 2022 - nature.com
Supramolecular polymer networks are non-covalently crosslinked soft materials that exhibit
unique mechanical features such as self-healing, high toughness and stretchability …

[HTML][HTML] Supramolecular engineering of hydrogels for drug delivery

S Bernhard, MW Tibbitt - Advanced Drug Delivery Reviews, 2021 - Elsevier
Supramolecular binding motifs are increasingly employed in the design of biomaterials. The
ability to rationally engineer specific yet reversible associations into polymer networks with …

Smart hydrogels in tissue engineering and regenerative medicine

S Mantha, S Pillai, P Khayambashi, A Upadhyay… - Materials, 2019 - mdpi.com
The field of regenerative medicine has tremendous potential for improved treatment
outcomes and has been stimulated by advances made in bioengineering over the last few …

Controlled drug delivery vehicles for cancer treatment and their performance

S Senapati, AK Mahanta, S Kumar… - Signal transduction and …, 2018 - nature.com
Although conventional chemotherapy has been successful to some extent, the main
drawbacks of chemotherapy are its poor bioavailability, high-dose requirements, adverse …

Self‐healing hydrogels: the next paradigm shift in tissue engineering?

S Talebian, M Mehrali, N Taebnia… - Advanced …, 2019 - Wiley Online Library
Given their durability and long‐term stability, self‐healable hydrogels have, in the past few
years, emerged as promising replacements for the many brittle hydrogels currently being …

Controllable C–H alkylation of polyethers via iron photocatalysis

Z Zhang, X Li, D Zhou, S Ding, M Wang… - Journal of the American …, 2023 - ACS Publications
The efficient conversion of a C–H bond in the polyether chain to other functional groups
provides great opportunities for development of novel applications in many research fields …