Pathophysiology, phenotypes and management of type 2 diabetes mellitus in Indian and Chinese populations

C Ke, KMV Narayan, JCN Chan, P Jha… - Nature Reviews …, 2022 - nature.com
Nearly half of all adults with type 2 diabetes mellitus (T2DM) live in India and China. These
populations have an underlying predisposition to deficient insulin secretion, which has a key …

Epidemiology and determinants of type 2 diabetes in south Asia

AP Hills, R Arena, K Khunti, CS Yajnik… - The lancet Diabetes & …, 2018 - thelancet.com
Type 2 diabetes has rapidly developed into a major public health problem in south Asia
(defined here as Bangladesh, Bhutan, India, Nepal, Pakistan, and Sri Lanka) in recent …

Type 2 diabetes mellitus, its impact on quality of life and how the disease can be managed-a review

P Garg, N Duggal - Obesity Medicine, 2022 - Elsevier
Background Diabetes is a complex metabolic disorder with multi factors playing complex
interactive functions. A severe effect of this disorder is observed in the quality of life in the …

Genetic variants of DNAH11 and LRFN2 genes and their association with ovarian and breast cancer

S Verma, D Bakshi, V Sharma, I Sharma… - … of Gynecology & …, 2020 - Wiley Online Library
Objective To investigate the association of newly identified genetic variants G> A
(rs2285947) of the DNAH 11 gene and G> A (rs2494938) of the LRFN 2 gene with ovarian …

Transmembrane 163 (TMEM163) protein: a new member of the zinc efflux transporter family

DJ Styrpejko, MP Cuajungco - Biomedicines, 2021 - mdpi.com
A growing body of evidence continues to demonstrate the vital roles that zinc and its
transporters play on human health. The mammalian solute carrier 30 (SLC30) family, with …

[HTML][HTML] Preliminary genome wide screening identifies new variants associated with coronary artery disease in Indian population

KG Bhat, VS Guleria, G Rastogi, V Sharma… - American Journal of …, 2022 - ncbi.nlm.nih.gov
Aim: Coronary artery disease (CAD) is a major health problem in developed and developing
nations. Development of CAD involves a complex interaction between genetics and lifestyle …

Functional interdependence of the actin nucleator Cobl and Cobl-like in dendritic arbor development

M Izadi, E Seemann, D Schlobinski, L Schwintzer… - Elife, 2021 - elifesciences.org
Local actin filament formation is indispensable for development of the dendritic arbor of
neurons. We show that, surprisingly, the action of single actin filament-promoting factors was …

Cobl-like promotes actin filament formation and dendritic branching using only a single WH2 domain

M Izadi, D Schlobinski, M Lahr, L Schwintzer… - Journal of Cell …, 2018 - rupress.org
Local actin filament formation powers the development of the signal-receiving arbor of
neurons that underlies neuronal network formation. Yet, little is known about the molecules …

COBLL1 and IRS1 Gene Polymorphisms and Placental Expression in Women with Gestational Diabetes

P Ustianowski, D Malinowski, M Czerewaty… - Biomedicines, 2022 - mdpi.com
Gestational diabetes mellitus (GDM) is carbohydrate intolerance in pregnant women leading
to various complications. Currently, there is a search for factors predisposing to GDM …

[HTML][HTML] Empirical assessment of allele frequencies of genome wide association study variants associated with obstructive sleep apnea

I Sharma, V Sharma, S Kumar, G Rastogi… - American journal of …, 2022 - ncbi.nlm.nih.gov
Objective: Obstructive Sleep Apnea (OSA) is a heterogeneous disorder with a complex
interplay of genetic and environmental factors. Over the years, with advancement in …