Exercise perturbs homeostasis, alters the levels of circulating mediators and hormones, and
increases the demand by skeletal muscles and other vital organs for energy substrates …

Intermittent administration of parathyroid hormone (PTH) stimulates bone formation by
increasing osteoblast number, but the molecular and cellular mechanisms underlying this …

Parathyroid hormone (PTH) is the major secretory product of the chief cells of the
parathyroid glands, and the human gene encoding PTH is located on chromosome 11. 1 …

Parathyroid hormone (PTH) regulates calcium homeostasis via the type I PTH/PTH-related
peptide (PTH/PTHrP) receptor (PTH1R). The purpose of the present study was to identify the …

Parathyroid hormone (PTH) is an 84-amino-acid polypeptide hormone functioning as a
major mediator of bone remodeling and as an essential regulator of calcium homeostasis …

PTH is a major systemic regulator of the concentrations of calcium, phosphate, and active
vitamin D metabolites in blood and of cellular activity in bone. Intermittently administered …

The role of CTGF/CCN2 in osteolytic metastasis by breast cancer cells and its mechanism of
action were studied. Osteolytic metastasis accompanied by CCN2 and PTHrP …

Since the discovery of the link between mutations in the LRP5 gene and human bone mass,
considerable progress has been made in our understanding of Wnt signalling and bone …

Parathyroid hormone (PTH) binds to its receptor PTH1R (parathyroid hormone 1 receptor) in
osteoblastic cells to regulate bone remodeling and calcium homeostasis. While prolonged …

The RUNX family members play pivotal roles in normal development and neoplasia. RUNX1
and RUNX2 are essential for hematopoiesis and osteogenesis, respectively, while RUNX3 …