[HTML][HTML] Therapy Targeted to the NLRP3 Inflammasome in Chronic Kidney Disease

Y Ji, H Hua, Z Jia, A Zhang, G Ding - Kidney Diseases, 2024 - karger.com
Background: The NLRP3 inflammasome is a cytoplasmic polymeric protein complex
composed of the cytoplasmic sensor NLRP3, the apoptosis-related spot-like protein ASC …

Dimethyl itaconate is effective in host-directed antimicrobial responses against mycobacterial infections through multifaceted innate immune pathways

YJ Kim, EJ Park, SH Lee, P Silwal, JK Kim, JS Yang… - Cell & Bioscience, 2023 - Springer
Background Itaconate, a crucial immunometabolite, plays a critical role in linking immune
and metabolic functions to influence host defense and inflammation. Due to its polar …

Caracterización funcional de una nueva familia de péptidos bioactivos derivados de filamentos intermedios y estudio de sus posibles aplicaciones en salud humana

R Piñera-Moreno - 2024 - ddd.uab.cat
Aquest projecte va començar a partir de la troballa fortuïta per part del grup del Dr. Joan
Verdaguer (Universitat de Lleida) d'un pèptid anomenat DIF-P, derivat de la periferina, que …