Deep learning in histopathology: the path to the clinic

J Van der Laak, G Litjens, F Ciompi - Nature medicine, 2021 - nature.com
Abstract Machine learning techniques have great potential to improve medical diagnostics,
offering ways to improve accuracy, reproducibility and speed, and to ease workloads for …

Deep neural network models for computational histopathology: A survey

CL Srinidhi, O Ciga, AL Martel - Medical image analysis, 2021 - Elsevier
Histopathological images contain rich phenotypic information that can be used to monitor
underlying mechanisms contributing to disease progression and patient survival outcomes …

Scaling vision transformers to gigapixel images via hierarchical self-supervised learning

RJ Chen, C Chen, Y Li, TY Chen… - Proceedings of the …, 2022 - openaccess.thecvf.com
Abstract Vision Transformers (ViTs) and their multi-scale and hierarchical variations have
been successful at capturing image representations but their use has been generally …

Dtfd-mil: Double-tier feature distillation multiple instance learning for histopathology whole slide image classification

H Zhang, Y Meng, Y Zhao, Y Qiao… - Proceedings of the …, 2022 - openaccess.thecvf.com
Multiple instance learning (MIL) has been increasingly used in the classification of
histopathology whole slide images (WSIs). However, MIL approaches for this specific …

Transmil: Transformer based correlated multiple instance learning for whole slide image classification

Z Shao, H Bian, Y Chen, Y Wang… - Advances in neural …, 2021 - proceedings.neurips.cc
Multiple instance learning (MIL) is a powerful tool to solve the weakly supervised
classification in whole slide image (WSI) based pathology diagnosis. However, the current …

Multimodal co-attention transformer for survival prediction in gigapixel whole slide images

RJ Chen, MY Lu, WH Weng, TY Chen… - Proceedings of the …, 2021 - openaccess.thecvf.com
Survival outcome prediction is a challenging weakly-supervised and ordinal regression task
in computational pathology that involves modeling complex interactions within the tumor …

Interventional bag multi-instance learning on whole-slide pathological images

T Lin, Z Yu, H Hu, Y Xu… - Proceedings of the IEEE …, 2023 - openaccess.thecvf.com
Multi-instance learning (MIL) is an effective paradigm for whole-slide pathological images
(WSIs) classification to handle the gigapixel resolution and slide-level label. Prevailing MIL …

Multiple instance learning framework with masked hard instance mining for whole slide image classification

W Tang, S Huang, X Zhang, F Zhou… - Proceedings of the …, 2023 - openaccess.thecvf.com
The whole slide image (WSI) classification is often formulated as a multiple instance
learning (MIL) problem. Since the positive tissue is only a small fraction of the gigapixel WSI …

Predicting lymph node metastasis using histopathological images based on multiple instance learning with deep graph convolution

Y Zhao, F Yang, Y Fang, H Liu… - Proceedings of the …, 2020 - openaccess.thecvf.com
Multiple instance learning (MIL) is a typical weakly-supervised learning method where the
label is associated with a bag of instances instead of a single instance. Despite extensive …

Application of artificial intelligence in pathology: trends and challenges

I Kim, K Kang, Y Song, TJ Kim - Diagnostics, 2022 - mdpi.com
Given the recent success of artificial intelligence (AI) in computer vision applications, many
pathologists anticipate that AI will be able to assist them in a variety of digital pathology …