Neutrophils as protagonists and targets in chronic inflammation

O Soehnlein, S Steffens, A Hidalgo… - Nature Reviews …, 2017 - nature.com
Traditionally, neutrophils have been acknowledged to be the first immune cells that are
recruited to an inflamed tissue and have mainly been considered in the context of acute …

Mechanism of generation of oxidative stress and pathophysiology of type 2 diabetes mellitus: how are they interlinked?

K Rehman, MSH Akash - Journal of cellular biochemistry, 2017 - Wiley Online Library
Oxidative stress has been considered as a major hallmark for the pathogenesis and
development of type 2 diabetes mellitus (T2DM), but still it is debatable whether it is a mere …

Hyperlipidemia-triggered neutrophilia promotes early atherosclerosis

M Drechsler, RTA Megens, M van Zandvoort, C Weber… - Circulation, 2010 - Am Heart Assoc
Background—Inflammation and activation of immune cells are key mechanisms in the
development of atherosclerosis. Previous data indicate important roles for monocytes and T …

Multiple roles for neutrophils in atherosclerosis

O Soehnlein - Circulation research, 2012 - Am Heart Assoc
Because of their rare detection in atherosclerotic lesions, the involvement of neutrophils in
the pathophysiology of atherosclerosis has been largely denied. However, over the past …

The potential role of lycopene for human health.

H Gerster - Journal of the American College of Nutrition, 1997 - Taylor & Francis
Lycopene is one of the major carotenoids in Western diets and is found almost exclusively in
tomatoes and tomato products. It accounts for about 50% of carotenoids in human serum …

Lipid peroxidation cannot be used as a universal criterion of oxidative stress

Y Dotan, D Lichtenberg, I Pinchuk - Progress in lipid research, 2004 - Elsevier
Oxidative stress is a term used to denote the imbalance between the concentrations of
reactive oxygen and nitrogen species and the defense mechanisms of the body. Although it …

A novel component of the metabolic syndrome: the oxidative stress

E Hopps, D Noto, G Caimi, MR Averna - Nutrition, Metabolism and …, 2010 - Elsevier
The metabolic syndrome (MS) represents a cluster of cardiovascular (CV) risk factors
associated to CV disease and type 2 diabetes. It is still under debate whether MS is a mere …

Antioxidants in cardiovascular therapy: panacea or false hope?

K Goszcz, SJ Deakin, GG Duthie, D Stewart… - Frontiers in …, 2015 - frontiersin.org
Oxidative stress is a key feature of the atherothrombotic process involved in the etiology of
heart attacks, ischemic strokes, and peripheral arterial disease. It stands to reason that …

Organ-specific mechanisms of transendothelial neutrophil migration in the lung, liver, kidney, and aorta

SL Maas, O Soehnlein, JR Viola - Frontiers in immunology, 2018 - frontiersin.org
Immune responses are dependent on the recruitment of leukocytes to the site of
inflammation. The classical leukocyte recruitment cascade, consisting of capture, rolling …

Evaluation of scavenging activity assessed by Co (II)/EDTA-induced luminol chemiluminescence and DPPH·(2, 2-diphenyl-1-picrylhydrazyl) free radical assay

I Parejo, C Codina, C Petrakis, P Kefalas - Journal of Pharmacological and …, 2000 - Elsevier
The scavenging activities of three standard antioxidants, quercetin, ascorbic acid, and trolox,
were evaluated by Co (II)/ethylenediamine-tetraacetic acid (EDTA)-induced luminol …