Even though cancer treatment has improved over the recent decades, still more specific and
effective treatment concepts are mandatory. Surgical removal is not always possible …

Much of what is currently known concerning microtubule biochemistry and physiology has
come from studies of the interaction of various plant alkaloids with microtubules. This …

The differentiation of 3T3-F442A cells is accompanied by changes in cell morphology,
decreased synthesis and assembly of cytoskeletal proteins, and increased biosynthesis of …

Nerve growth factor (NGF) regulates the microtubule-dependent extension and maintenance
of axons by some peripheral neurons. We show here that one effect of NGF is to promote …

This volume brings together all aspects of TAXOL® research, development, and clinical use.
It provides comprehensive knowledge of the compound and a perspective of the complex …

Freshly isolated adult rat hepatocytes exhibit a flat, extended morphology when cultured on
dried rat tail collagen in the presence of growth factors; they actively synthesize DNA and …

During the formation of the mitotic spindle, dynamic microtubules search for chromosomes in
the surrounding cytosol. The average time required to reach such" targets" is calculated …

Microfiltration is a ubiquitous and often crucial part of many industrial processes, including
biopharmaceutical manufacturing. Yet, all existing filtration systems suffer from the issue of …

The differentiation of 3T3-F442A preadipocytes is characterized by numerous enzymatic
events and by'a programmed change in cell morphology from a fibroblastic form to a nearly …

Although numerous studies have suggested ways in which the assembly of cytoskeletal
proteins can be regulated physiologically, less information has been generated on the …