Bacteria have developed diverse strategies for defending their cell envelopes from external
threats. In Firmicutes, one widespread strategy is to use Bce modules—membrane protein …

Cilagicin is a Gram-positive active antibiotic that has a dual polyprenyl phosphate binding
mechanism that impedes resistance development. Here we bioinformatically screened …

The continued rise of antibiotic resistance is a global concern that threatens to undermine
many aspects of modern medical practice. Key to addressing this threat is the discovery and …

The prevalence of drug‐resistant bacterial pathogens foreshadows a healthcare crisis.
Calcium‐dependent antibiotics (CDAs) are promising candidates to combat infectious …

摘要拉斯帕托霉素C (Laspartomycin C, LspC) 是被最廣泛研究的鈣依賴型抗生素(Calcium-
dependent antibiotic, CDA) 之一. 在之前已有關於LspC 的晶體研究, 在研究中已經證實了LspC …

抄録 Recently, the antibacterial effects of essential oils have been investigated in addition to
their therapeutic purposes. Owing to their hydrophobic nature, they are thought to perturb …

Antibacterial resistant infections are an ongoing global health emergency. To combat this,
novel potent antibiotics with unique modes of action are required. The classic arsenal of …

In Lactococcus lactis, different regulation mechanisms can be activated to overcome the
effects of adverse environmental stresses. Here, a TetR family regulator LssR was …

The continued rise of antibiotic resistance is a global concern that threatens to undermine
many aspects of modern medical practice. Key to addressing this threat is the discovery and …