Homeostasis of the gut barrier and potential biomarkers
The gut barrier plays a crucial role by spatially compartmentalizing bacteria to the lumen
through the production of secreted mucus and is fortified by the production of secretory IgA …
through the production of secreted mucus and is fortified by the production of secretory IgA …
Toll-like receptors in inflammatory bowel diseases: a decade later
E Cario - Inflammatory bowel diseases, 2010 - academic.oup.com
Differential alteration of Toll-like receptor (TLR) expression in inflammatory bowel disease
(IBD) was first described 10 years ago. Since then, studies from many groups have led to the …
(IBD) was first described 10 years ago. Since then, studies from many groups have led to the …
Airway gland structure and function
JH Widdicombe, JJ Wine - Physiological reviews, 2015 - journals.physiology.org
Submucosal glands contribute to airway surface liquid (ASL), a film that protects all airway
surfaces. Glandular mucus comprises electrolytes, water, the gel-forming mucin MUC5B …
surfaces. Glandular mucus comprises electrolytes, water, the gel-forming mucin MUC5B …
Gastrointestinal and hepatic mechanisms limiting entry and dissemination of lipopolysaccharide into the systemic circulation
M Guerville, G Boudry - American Journal of Physiology …, 2016 - journals.physiology.org
The human microbiota consists of 100 trillion microorganisms that provide important
metabolic and biological functions benefiting the host. However, the presence in host …
metabolic and biological functions benefiting the host. However, the presence in host …
Bacteria in the intestine, helpful residents or enemies from within?
GO Canny, BA McCormick - Infection and immunity, 2008 - Am Soc Microbiol
Humans evolved in the presence of numerous microbial communities that preceded the
appearance of mammals on planet Earth. The role of these microbial communities in our …
appearance of mammals on planet Earth. The role of these microbial communities in our …
Role of innate immunity in neonatal infection
AG Cuenca, JL Wynn, LL Moldawer… - American journal of …, 2013 - thieme-connect.com
Newborns are at increased risk of infection due to genetic, epigenetic, and environmental
factors. Herein we examine the roles of the neonatal innate immune system in host defense …
factors. Herein we examine the roles of the neonatal innate immune system in host defense …
Inflammatory bowel disease: an impaired barrier disease
Background The intestinal barrier is a delicate structure composed of a single layer of
epithelial cells, the mucus, commensal bacteria, immune cells, and antibodies. Furthermore …
epithelial cells, the mucus, commensal bacteria, immune cells, and antibodies. Furthermore …
Defensins and other antimicrobial peptides in inflammatory bowel disease
Defensins and other antimicrobial peptides in inflammatory b... : Current Opinion in
Gastroenterology Defensins and other antimicrobial peptides in inflammatory bowel disease …
Gastroenterology Defensins and other antimicrobial peptides in inflammatory bowel disease …
[HTML][HTML] New insights into lipopolysaccharide inactivation mechanisms in sepsis
EG Pérez-Hernández, B Delgado-Coello… - Biomedicine & …, 2021 - Elsevier
The complex pathophysiology of sepsis makes it a syndrome with limited therapeutic options
and a high mortality rate. Gram-negative bacteria containing lipopolysaccharides (LPS) in …
and a high mortality rate. Gram-negative bacteria containing lipopolysaccharides (LPS) in …
[HTML][HTML] Barrier dysfunction due to distinct defensin deficiencies in small intestinal and colonic Crohn's disease
Defensins are endogenous antibiotics with broad microbicidal activity. A disturbed
antimicrobial defense, as provided by Paneth and other epithelial defensins, seems to be a …
antimicrobial defense, as provided by Paneth and other epithelial defensins, seems to be a …