The role of inflammasomes in vascular cognitive impairment

L Poh, WL Sim, DG Jo, QN Dinh, GR Drummond… - Molecular …, 2022 - Springer
There is an increasing prevalence of Vascular Cognitive Impairment (VCI) worldwide, and
several studies have suggested that Chronic Cerebral Hypoperfusion (CCH) plays a critical …

Nrf2—a promising therapeutic target for defensing against oxidative stress in stroke

R Zhang, M Xu, Y Wang, F Xie, G Zhang, X Qin - Molecular Neurobiology, 2017 - Springer
Stroke is one of the leading causes of death and disability in the world. Oxidative stress,
which refers to an excessive generation of reactive oxygen species (ROS), plays a key role …

Pathogenesis of acute stroke and the role of inflammasomes

DYW Fann, SY Lee, S Manzanero, P Chunduri… - Ageing research …, 2013 - Elsevier
Inflammation is an innate immune response to infection or tissue damage that is designed to
limit harm to the host, but contributes significantly to ischemic brain injury following stroke …

Oxidative stress: a suitable therapeutic target for optic nerve diseases?

F Buonfiglio, EW Böhm, N Pfeiffer, A Gericke - Antioxidants, 2023 - mdpi.com
Optic nerve disorders encompass a wide spectrum of conditions characterized by the loss of
retinal ganglion cells (RGCs) and subsequent degeneration of the optic nerve. The etiology …

Role of uric acid metabolism‐related inflammation in the pathogenesis of metabolic syndrome components such as atherosclerosis and nonalcoholic steatohepatitis

A Kushiyama, Y Nakatsu, Y Matsunaga… - Mediators of …, 2016 - Wiley Online Library
Uric acid (UA) is the end product of purine metabolism and can reportedly act as an
antioxidant. However, recently, numerous clinical and basic research approaches have …

Role of oxidative stress in ocular diseases associated with retinal ganglion cells degeneration

EYC Kang, PK Liu, YT Wen, PMJ Quinn, SR Levi… - Antioxidants, 2021 - mdpi.com
Ocular diseases associated with retinal ganglion cell (RGC) degeneration is the most
common neurodegenerative disorder that causes irreversible blindness worldwide. It is …

Iron/iron oxide-based magneto-electrochemical sensors/biosensors for ensuring food safety: recent progress and challenges in environmental protection

M Adampourezare, M Hasanzadeh… - RSC …, 2023 - pubs.rsc.org
Foodborne diseases have arisen due to the globalization of industry and the increase in
urban population, which has led to increased demand for food and has ultimately …

Targeting oxidative stress for the treatment of ischemic stroke: Upstream and downstream therapeutic strategies

W Li, S Yang - Brain circulation, 2016 - journals.lww.com
Excessive oxygen and its chemical derivatives, namely reactive oxygen species (ROS),
produce oxidative stress that has been known to lead to cell injury in ischemic stroke. ROS …

Effects of natural polyphenols on oxidative stress-mediated blood-brain barrier dysfunction

Y Kim, AY Cho, HC Kim, D Ryu, SA Jo, YS Jung - antioxidants, 2022 - mdpi.com
The blood-brain barrier (BBB), which consists mainly of brain microvascular endothelial cells
and astrocytes connected by tight junctions (TJs) and adhesion molecules (AMs), maintains …

Detection of xanthine in food samples with an electrochemical biosensor based on PEDOT: PSS and functionalized gold nanoparticles

MZH Khan, MS Ahommed, M Daizy - RSC advances, 2020 - pubs.rsc.org
An innovative biosensor assembly relying on glassy carbon electrodes modified with
nanocomposites consisting of poly (3, 4-ethylenedioxythiophene) polystyrene sulfonate …