In silico, defined in analogy to in vitro and in vivo as those studies that are performed on a
computer, is an essential step in problem-solving and product development in classical …

Strain energy density (SED) is considered to be the primary remodelling stimulus influencing
the process of bone growth into porous implants. A bone remodelling algorithm …

In recent years, the patient specific medical scenario has gained increasing popularity in
health and engineering research. Unlike the standard medical paradigm (generalized …

Bone remodelling models are widely used in a phenomenological manner to estimate
numerically the distribution of apparent density in bones from the loads they are daily …

This paper presents a framework for modelling biological tissues based on discrete
particles. Cell components (eg cell membranes, cell cytoskeleton, cell nucleus) and …

摘要背景: 随着老龄化的加剧, 骨质疏松性髋部骨折的发生率及死亡率上升,
研究其发病机制和防治方法具有重大意义. 目前应用有限元分析法判断骨折的依据仅限于骨折 …

Tooth movement, as it is generally visualized by orthodontist clinicians, is modeled as a
biological event mediated by the cells of the periodontal ligament (PDL) whereby alveolar …

In finite element simulations of orthodontic tooth movement, one of the challenges is to
represent long term tooth movement. Large deformation of the periodontal ligament and …

Many hypotheses have been formulated to explain orthodontic tooth movement. However,
none of them can satisfactorily explain how small static orthodontic forces can induce bone …

Computational modeling of skeletal tissue seeks to predict the structural adaptation of bone
in response to mechanical loading. The theory of continuum damage–repair, a mathematical …