DNA methylation meningioma biomarkers: attributes and limitations

Z Li, Y Gao, J Zhang, L Han, H Zhao - Frontiers in Molecular …, 2023 - frontiersin.org
Meningioma, one of the most common primary central nervous system tumors, are classified
into three grades by the World Health Organization (WHO) based on histopathology. The …

Clinical significance of molecular alterations and systemic therapy for meningiomas: where do we stand?

A Pellerino, F Bruno, R Palmiero, E Pronello, L Bertero… - Cancers, 2022 - mdpi.com
Simple Summary Meningiomas are the most frequent intracranial tumors and comprise a
heterogeneous spectrum of diseases, ranging from small, asymptomatic tumors that do not …

Molecular neuropathology: an essential and evolving toolbox for the diagnosis and clinical management of central nervous system tumors

L Bertero, L Mangherini, AA Ricci, P Cassoni, F Sahm - Virchows Archiv, 2024 - Springer
Molecular profiling has transformed the diagnostic workflow of CNS tumors during the last
years. The latest WHO classification of CNS tumors (5th edition), published in 2021, pushed …

Update on the diagnosis and management of meningiomas

F Maiuri, M Del Basso de Caro - Cancers, 2023 - mdpi.com
This series of five articles (one original article and four reviews) focuses on the most recent
and interesting research studies on the biomolecular and radiological diagnosis and the …

Somatostatin analogues in treatment-refractory meningioma: a systematic review with meta-analysis of individual patient data

LR Jensen, AD Maier, A Lomstein, T Graillon… - Neurosurgical …, 2022 - Springer
Abstract Treatment-refractory meningiomas have a dismal prognosis and limited treatment
options. Meningiomas express high-densities of somatostatin receptors (SSTR), thus …

Molecular landscapes of longitudinal NF2/22q and non‐NF2/22q meningiomas show different life histories

HK Ng, KKW Li, NYF Chung, JYT Chan… - Brain …, 2023 - Wiley Online Library
Recurrence is a major complication of some meningiomas. Although there were many
studies on biomarkers associated with higher grades or increased aggressiveness, few …

Pathology of the Tumors of the Central Nervous System

R Bumci, I Parthymos, C Zamboglou… - Intraoperative Flow …, 2023 - Springer
Up until the fourth edition of World Health Organization (WHO) Classification of Central
Nervous System (CNS) Tumors which was published in 2016, definitions of the tumor …

Biomolecular-Related Medical Therapy for Meningiomas

A Pellerino, F Bruno, E Pronello, R Rudà… - … : From Pathology to …, 2024 - Springer
Patients with progressive or recurrent meningiomas failing all surgical and radiotherapeutic
treatment options or patients with meningiomas in surgically challenging areas, such as the …

GAB1 as a Marker of Recurrence in Anterior Skull Base Meningioma

J Boetto, F Bielle, S Tran, P Marijon, M Peyre… - …, 2023 - journals.lww.com
BACKGROUND: About one-third of anterior skull base meningiomas show Hedgehog
pathway activation. We have recently identified GAB1 as a surrogate marker for Hedgehog …

Comprehensive Overview of Genetic Alterations in Meningioma

SLN Maas, F Sahm, TA Juratli - Meningiomas: From Pathology to Clinics, 2024 - Springer
Meningiomas are the most common intracranial tumors in adult patients. According to the
World Health Organization (WHO) criteria, meningiomas are classified into grades 1 to 3 for …