Ets1 belongs to the large family of the ETS domain family of transcription factors and is
involved in cancer progression. In most carcinomas, Ets1 expression is linked to poor …

Reactive oxygen species (ROS) are closely related to tumorgenesis. Under hypoxic
environment, increased levels of ROS induce the expression of hypoxia inducible factors …

Lymph node metastasis, the leading cause of mortality in esophageal squamous carcinoma
(ESCC) with a highly complex tumor microenvironment, remains underexplored. Here, the …

Epithelial ovarian cancer (EOC) is the most lethal gynecological malignancy in the
developed world. EOC metastasis is unique since malignant cells detach directly from the …

Head and neck cancer (HNC) is the six most common malignancy worldwide leading to
more than 350,000 deaths annually. Despite recent advances in treatment modalities for …

Anchored cells of the basal epidermis constantly undergo proliferation in an overcrowded
environment. An important regulator of epidermal proliferation is YAP, which can be …

CD90 is a membrane GPI-anchored protein with one Ig V-type superfamily domain that was
initially described in mouse T cells. Besides the specific expression pattern and functions of …

Esophageal cancer is one of the most lethal cancers worldwide with poor survival and
limited therapeutic options. The discovery of microRNAs created a new milestone in cancer …

Abstract THY1 (CD90) is a 25–37-kDa heavily N-glycosylated, glycophosphatidylinositol
(GPI) anchored cell surface protein. It is usually expressed on thymocytes, mesenchymal …

Invasion and metastasis are the major cause of deaths in patients with esophageal cancer.
In this study, we isolated cancer stem-like cells from an esophageal squamous cell …