FDA approved drugs with pharmacotherapeutic potential for SARS-CoV-2 (COVID-19) therapy

S Drożdżal, J Rosik, K Lechowicz, F Machaj… - Drug resistance …, 2020 - Elsevier
In December 2019, a novel SARS-CoV-2 coronavirus emerged, causing an outbreak of life-
threatening pneumonia in the Hubei province, China, and has now spread worldwide …

Molecular dynamics simulation approach for discovering potential inhibitors against SARS-CoV-2: A structural review

S Ghahremanian, MM Rashidi, K Raeisi… - Journal of molecular …, 2022 - Elsevier
Since the commencement of the novel Coronavirus, the disease has quickly turned into a
worldwide crisis so that there has been growing attention in discovering possible hit …

[HTML][HTML] Drug repurposing approach against novel coronavirus disease (COVID-19) through virtual screening targeting SARS-CoV-2 main protease

KH Chowdhury, MR Chowdhury, S Mahmud, AM Tareq… - Biology, 2021 - mdpi.com
Abstract Novel coronavirus disease (COVID-19) was identified from China in December
2019 and spread rapidly through human-to-human transmission, affecting so many people …

Development of vaccine formulations: past, present, and future

C D'Amico, F Fontana, R Cheng, HA Santos - Drug Delivery and …, 2021 - Springer
The current situation, heavily influenced by the ongoing pandemic, puts vaccines back into
the spotlight. However, the conventional and traditional vaccines present disadvantages …

Repurposing drugs for the management of COVID-19

J Cusinato, Y Cau, AM Calvani… - Expert opinion on …, 2021 - Taylor & Francis
Introduction: The coronavirus disease 2019 (COVID-19) caused by SARS-CoV-2 represents
a serious health issue worldwide, with more than 61 million cases and more than 1.4 million …

COVID‐19: A systematic review and update on prevention, diagnosis, and treatment

H Aghamirza Moghim Aliabadi… - MedComm, 2022 - Wiley Online Library
Since the rapid onset of the COVID‐19 or SARS‐CoV‐2 pandemic in the world in 2019,
extensive studies have been conducted to unveil the behavior and emission pattern of the …

Potential RNA-dependent RNA polymerase (RdRp) inhibitors as prospective drug candidates for SARS-CoV-2

MS Bekheit, SS Panda, AS Girgis - European Journal of Medicinal …, 2023 - Elsevier
The SARS-CoV-2 pandemic is considered as one of the most disastrous pandemics for
human health and the world economy. RNA-dependent RNA polymerase (RdRp) is one of …

A blueprint for high affinity SARS-CoV-2 Mpro inhibitors from activity-based compound library screening guided by analysis of protein dynamics

J Gossen, S Albani, A Hanke, BP Joseph… - ACS pharmacology & …, 2021 - ACS Publications
The SARS-CoV-2 coronavirus outbreak continues to spread at a rapid rate worldwide. The
main protease (Mpro) is an attractive target for anti-COVID-19 agents. Unexpected …

A Patent Review on SARS Coronavirus Main Protease (3CLpro) Inhibitors

CSB Chia, W Xu, P Shuyi Ng - ChemMedChem, 2022 - Wiley Online Library
The severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) pandemic is an
unprecedented global health emergency causing more than 4.2 million fatalities as of 30 …

The inclusive review on SARS-CoV-2 biology, epidemiology, diagnosis, and potential management options

A Beig Parikhani, M Bazaz, H Bamehr, S Fereshteh… - Current …, 2021 - Springer
A novel coronavirus member was reported in Wuhan City, Hubei Province, China, at the end
of the year 2019. Initially, the infection spread locally, affecting the Wuhan people, and then …