The challenges in the diagnosis, prognosis, and monitoring of Gaucher disease (GD), an
autosomal recessive inborn error of glycosphingolipid metabolism, can negatively impact …

Plants contain numerous glycoconjugates that are metabolized by specific
glucosyltransferases and hydrolyzed by specific glycosidases, some also catalyzing …

Mutations in the GBA1 gene are the most common genetic risk factor for Parkinson's disease
(PD) and dementia with Lewy bodies (DLB). GBA1 encodes the lysosomal lipid hydrolase …

Rheumatoid arthritis (RA) is a chronic autoimmune condition characterized by inflammatory
activity with distinct rhythmic fluctuations. However, the precise mechanisms governing …

Globally, the demands for sustainably sourced functional foods like prebiotic
oligosaccharides have been constantly increasing. This study assessed the potential of …

Glycosphingolipids are important building blocks of the outer leaflet of the cell membrane.
They are continuously recycled, involving fragmentation inside lysosomes by glycosidases …

Biallelic mutations in the glucocerebrosidase (GBA1) gene cause Gaucher disease,
characterized by lysosomal accumulation of glucosylceramide and glucosylsphingosine in …

Gaucher disease (GD), the most prevalent lysosomal disorder, is caused by GBA1 gene
mutations, leading to deficiency of glucocerebrosidase, and accumulation of …

In this study, a Eucalyptus by-product was fractionated into cellulose and lignin by
pretreatment with NaClO 2 to obtain α-cellulose, and hydrothermal pretreatment followed by …

Epoxide functional group is a part of several natural as well as synthetic compounds.
Irrespective of the role of epoxide group in drug efficacy and the use of epoxide compounds …