Therapeutic strategies to target the androgen receptor
The androgen receptor (AR) plays a key role in the maintenance of muscle and bone and
the support of male sexual-related functions, as well as in the progression of prostate …
the support of male sexual-related functions, as well as in the progression of prostate …
Regulation of anti-Müllerian hormone (AMH) in males and the associations of serum AMH with the disorders of male fertility
HY Xu, HX Zhang, Z Xiao, J Qiao… - Asian journal of andrology, 2019 - journals.lww.com
Anti-Müllerian hormone (AMH) is a functional marker of fetal Sertoli cells. The germ cell
number in adults depends on the number of Sertoli cells produced during perinatal …
number in adults depends on the number of Sertoli cells produced during perinatal …
What does androgen receptor signaling pathway in sertoli cells during normal spermatogenesis tell us?
JM Wang, ZF Li, WX Yang - Frontiers in Endocrinology, 2022 - frontiersin.org
Androgen receptor signaling pathway is necessary to complete spermatogenesis in testes.
Difference between androgen binding location in Sertoli cell classifies androgen receptor …
Difference between androgen binding location in Sertoli cell classifies androgen receptor …
Reproductive aging in male dogs: The epididymal sperm defects and expression of androgen receptor in reproductive tissues
C Bhanmeechao, S Srisuwatanasagul, N Prapaiwan… - Theriogenology, 2018 - Elsevier
The present study aimed at investigating age-related changes in epididymal sperm motility,
morphology, DNA integrity and androgen receptor (AR) expression in canine reproductive …
morphology, DNA integrity and androgen receptor (AR) expression in canine reproductive …
Novel pathogenic variants in the androgen receptor gene associated with androgen insensitivity syndrome identified through exome sequencing and in silico analysis
C Li, X Wang, X Wang, X Li, W Chen, M Zhao, X Liu… - Gene, 2023 - Elsevier
Androgen insensitivity syndrome (AIS) is a common disorder/differences of sex development
with a 46, XY karyotype, but diverse genital phenotypes. Various pathogenic variants within …
with a 46, XY karyotype, but diverse genital phenotypes. Various pathogenic variants within …
[PDF][PDF] USP26 deubiquitinates androgen receptor (AR) in the maintenance of sperm maturation and spermatogenesis through the androgen receptor signaling …
J Wang, X Zhao, R Hong, J Wang - Adv Clin Exp Med, 2020 - dbc.wroc.pl
Background. The post-translational modifications of proteins control various physiological
and pathological events in cells. Objectives. In this study, we investigated the influences of …
and pathological events in cells. Objectives. In this study, we investigated the influences of …
Complete androgen insensitivity syndrome due to mutations in the DNA-binding domain of the human androgen receptor gene
Androgen insensitivity syndrome (AIS) is an X-linked recessive disorder with a 46, XY
karyotype caused by alterations in the androgen receptor (AR) gene. We have identified 2 …
karyotype caused by alterations in the androgen receptor (AR) gene. We have identified 2 …
Effect of androgens on Sertoli cell maturation in human testis from birth to puberty
Background Androgens are well known to be necessary for spermatogenesis. The purpose
of this study was to determine Sertoli cell responsiveness to androgens according to age …
of this study was to determine Sertoli cell responsiveness to androgens according to age …
129 例辅助生殖技术子代儿童耳聋基因突变筛查.
孟晔， 陶媛媛， 胡馨， 桑美英… - Journal of International …, 2020 - search.ebscohost.com
目的: 了解辅助生殖技术(assisted reproductive technology, ART) 子代儿童常见遗传性耳聋
基因突变发生率. 方法: 随机选取2010 年1 月—2014 年12 月在中国科学技术大学附属第一医院 …
基因突变发生率. 方法: 随机选取2010 年1 月—2014 年12 月在中国科学技术大学附属第一医院 …
完全型雄激素不敏感综合征2 例临床特点及处理.
陶虹江， 陈捷， 陈小燕 - Journal of International …, 2020 - search.ebscohost.com
雄激素不敏感综合征(androgen insensitivity syndrome, AIS) 又称为睾丸女性化综合征(
testicular feminization syndrome, TFS), 是一种X 连锁遗传病, 是男性假两性畸形中较常见的 …
testicular feminization syndrome, TFS), 是一种X 连锁遗传病, 是男性假两性畸形中较常见的 …