Agmatine, an endogenous polyamine derived from L-arginine, elicits tremendous
multimodal neuromodulant properties. Alterations in agmatinergic signalling are closely …

Parasites of the genus Leishmania cause a variety of devastating and often fatal diseases in
humans and domestic animals worldwide. The need for new therapeutic strategies is urgent …

Covering: 2008 and 2009. Previous review: Nat. Prod. Rep., 2008, 25, 919 Organic
guanidine compounds are reviewed, with emphasis on natural product isolation …

A series of N-phenyl-substituted and disubstituted guanidinyl benzothiazole derivatives 4a–
4m were synthesized and characterized as novel antimicrobial and antioxidant agents. The …

There is an urgent need for the identification and validation of new therapeutic targets in
protozoan parasites because currently available drugs are limited in number and …

A series of N-pivaloyl-N′-(alkyl/aryl)-N ″-pyridylguanidine of general formula
C4H9CONHC (NR1R2) NPy have been synthesized and characterized using elemental …

A series of N, N′, N′′-trisubstituted guanidines (1–6) and their copper (II) complexes,[κ2
(O, N)-C6H5CONHC (NHC6H4Cl) NR] 2Cu (II)(R= iso-propyl (1a), n-butyl (2a), sec-butyl …

Alkylation of ethyl N-hydroxyacetimidate with readily available methanesulfonates of
functionally substituted alcohols and subsequent deprotection of aminooxy group is a novel …

Leishmaniasis are neglected infectious diseases caused by kinetoplastid protozoan
parasites from the genus Leishmania. These sicknesses are present mainly in tropical …

In trypanosomatids, redox homeostasis is centered on trypanothione (N1, N8-bis
(glutathionyl) spermidine, T (SH) 2), a low molecular weight thiol that is distinctive for this …