Beyond ATP: Metabolite networks as regulators of physiological and pathological erythroid differentiation
A Joly, A Schott, I Phadke… - …, 2025 - journals.physiology.org
Hematopoietic stem cells (HSCs) possess the capacity for self-renewal and the sustained
production of all mature blood cell lineages. It has been well established that a metabolic …
production of all mature blood cell lineages. It has been well established that a metabolic …
[HTML][HTML] A Bloody Feast–Nutritional Regulation of Hematopoiesis
N Ussishkin, D Nachmani - Experimental Hematology, 2023 - Elsevier
Hematopoietic stem cells provide us with a life-long supply of blood cells. Hence, their
proper function is absolutely essential for life, and their dysfunction can lead to infectious …
proper function is absolutely essential for life, and their dysfunction can lead to infectious …
Sex and organ specific proteomic responses to vitamin C deficiency in the brain, heart, liver, and spleen of Gulo-/- mice
L Aumailley, M Lebel - PloS one, 2024 - journals.plos.org
Recent advances in mass spectrometry have indicated that the water-soluble antioxidant
vitamin C differentially modulates the abundance of various proteins in the hepatic tissue of …
vitamin C differentially modulates the abundance of various proteins in the hepatic tissue of …
Ascorbate deficiency increases quiescence and self-renewal in hematopoietic stem cells and multipotent progenitors
S Comazzetto, DL Cassidy, AW DeVilbiss, EC Jeffery… - Blood, 2025 - ashpublications.org
Ascorbate (vitamin C) limits hematopoietic stem cell (HSC) function and suppresses
leukemia development, partly by promoting the function of the Tet2 tumor suppressor. In …
leukemia development, partly by promoting the function of the Tet2 tumor suppressor. In …
Scurvy: A treatable forgotten fatal differential diagnosis and potential etiology of leukemia and aplastic anemia in pediatric population
HL Mashauri - Health Science Reports, 2023 - Wiley Online Library
Scurvy is a rare nutritional deficiency disease which is less likely to be suspected and it
mostly lead to delayed diagnosis. It can present with features which can mislead clinicians to …
mostly lead to delayed diagnosis. It can present with features which can mislead clinicians to …
[HTML][HTML] Ascorbate depletion increases quiescence and self-renewal potential in hematopoietic stem cells and multipotent progenitors
S Comazzetto, DL Cassidy, AW DeVilbiss, EC Jeffery… - bioRxiv, 2024 - ncbi.nlm.nih.gov
Ascorbate (vitamin C) limits hematopoietic stem cell (HSC) function and suppresses
leukemia development by promoting the function of the Tet2 tumor suppressor. In humans …
leukemia development by promoting the function of the Tet2 tumor suppressor. In humans …
Ascorbic acid in cancer management–time for a second look
I Ogochukwu - 2023 - repozytorium.ur.edu.pl
Introduction and aim. Over the past decades, the hypotheses that ascorbic acid (AA) can
play a role as an anti-neoplastic therapy have generated many conflicting reports. Despite …
play a role as an anti-neoplastic therapy have generated many conflicting reports. Despite …