Metabolic diseases and healthy aging: identifying environmental and behavioral risk factors and promoting public health

K Zhang, Y Ma, Y Luo, Y Song, G Xiong, Y Ma… - Frontiers in Public …, 2023 - frontiersin.org
Aging is a progressive and irreversible pathophysiological process that manifests as the
decline in tissue and cellular functions, along with a significant increase in the risk of various …

Biomarkers of aging in real life: three questions on aging and the comprehensive geriatric assessment

M Zampino, MC Polidori, L Ferrucci, D O'Neill, A Pilotto… - GeroScience, 2022 - Springer
Measuring intrinsic, biological age is a central question in medicine, which scientists have
been trying to answer for decades. Age manifests itself differently in different individuals, and …

Causal association between basal metabolic rate and risk of cardiovascular diseases: a univariable and multivariable Mendelian randomization study

Y Li, H Zhai, L Kang, Q Chu, X Zhao, R Li - Scientific reports, 2023 - nature.com
Basal metabolic rate (BMR) is associated with cardiovascular health; however, the causal
relationship between BMR and the risk of cardiovascular diseases (CVDs) remains unclear …

Resting oxygen uptake value of 1 metabolic equivalent of task in older adults: a systematic review and descriptive analysis

J Leal-Martin, M Munoz-Munoz, SK Keadle… - Sports Medicine, 2022 - Springer
Background It is important for sport scientists and health professionals to have estimative
methods for energy demand during different physical activities. The metabolic equivalent of …

[HTML][HTML] Why does type 2 diabetes mellitus impair weight reduction in patients with obesity? A review

HE Bays - Obesity Pillars, 2023 - Elsevier
Background A common adiposopathic complication of obesity is type 2 diabetes mellitus.
Healthful weight reduction in patients with obesity can improve glucose metabolism and …

Gastrointestinal redox homeostasis in ageing

J Homolak - Biogerontology, 2023 - Springer
The gastrointestinal (GI) barrier acts as the primary interface between humans and the
external environment. It constantly faces the risk of inflammation and oxidative stress due to …

Effect of basal metabolic rate on lifespan: a sex-specific Mendelian randomization study

JCM Ng, CM Schooling - Scientific Reports, 2023 - nature.com
Observationally, the association of basal metabolic rate (BMR) with mortality is mixed,
although some ageing theories suggest that higher BMR should reduce lifespan. It remains …

Obesity and lifespan, a complex tango

A Diaz-Ruiz, NL Price, L Ferrucci… - Science Translational …, 2023 - science.org
Obesity and aging share comorbidities, phenotypes, and deleterious effects on health that
are associated with chronic diseases. However, distinct features set them apart, with …

Approach to obesity in the older population

A Buch, Y Marcus, G Shefer, P Zimmet… - The Journal of Clinical …, 2021 - academic.oup.com
Until recently, weight loss in older obese people was feared because of ensuing muscle loss
and frailty. Facing overall increasing longevity, high rates of obesity in older individuals …

Targeting the Hallmarks of Aging with Vitamin D: Starting to Decode the Myth

C Ruggiero, L Tafaro, L Cianferotti, F Tramontana… - Nutrients, 2024 - mdpi.com
Aging is the result of several complex and multifactorial processes, where several agents
contribute to an increased intrinsic vulnerability and susceptibility to age-related diseases …