Devising efficient red‐shifting strategies for bioimaging: A generalizable donor‐acceptor fluorophore prototype
Long emission wavelengths, high fluorescence quantum yields (FQYs), and large Stokes
shifts are highly desirable features for fluorescent probes in biological imaging. However …
shifts are highly desirable features for fluorescent probes in biological imaging. However …
Frontiers in multiscale modeling of photoreceptor proteins
This perspective article highlights the challenges in the theoretical description of
photoreceptor proteins using multiscale modeling, as discussed at the CECAM workshop in …
photoreceptor proteins using multiscale modeling, as discussed at the CECAM workshop in …
Retinal chromophore charge delocalization and confinement explain the extreme photophysics of Neorhodopsin
R Palombo, L Barneschi, L Pedraza-González… - Nature …, 2022 - nature.com
The understanding of how the rhodopsin sequence can be modified to exactly modulate the
spectroscopic properties of its retinal chromophore, is a prerequisite for the rational design …
spectroscopic properties of its retinal chromophore, is a prerequisite for the rational design …
Electrostatic control of photoisomerization pathways in proteins
Adam W. Duster1, Hai Lin2. 1Integrative and Systems Biology, University of Colorado
Denver, Denver, CO, USA, 2Chemistry, University of Colorado Denver, Denver, CO, USA …
Denver, Denver, CO, USA, 2Chemistry, University of Colorado Denver, Denver, CO, USA …
Directed evolution of a bright variant of mCherry: suppression of nonradiative decay by fluorescence lifetime selections
The approximately linear scaling of fluorescence quantum yield (ϕ) with fluorescence
lifetime (τ) in fluorescent proteins (FPs) has inspired engineering of brighter fluorophores …
lifetime (τ) in fluorescent proteins (FPs) has inspired engineering of brighter fluorophores …
Elucidating the role of hydrogen bonding in the optical spectroscopy of the solvated green fluorescent protein chromophore: Using machine learning to establish the …
Hydrogen bonding interactions with chromophores in chemical and biological environments
play a key role in determining their electronic absorption and relaxation processes, which …
play a key role in determining their electronic absorption and relaxation processes, which …
Internal conversion of the anionic GFP chromophore: in and out of the I-twisted S 1/S 0 conical intersection seam
NH List, CM Jones, TJ Martínez - Chemical Science, 2022 - pubs.rsc.org
The functional diversity of the green fluorescent protein (GFP) family is intimately connected
to the interplay between competing photo-induced transformations of the chromophore motif …
to the interplay between competing photo-induced transformations of the chromophore motif …
Conical intersection accessibility dictates brightness in red fluorescent proteins
Red fluorescent protein (RFP) variants are highly sought after for in vivo imaging since
longer wavelengths improve depth and contrast in fluorescence imaging. However, the …
longer wavelengths improve depth and contrast in fluorescence imaging. However, the …
Structural characterization of fluorescent proteins using tunable femtosecond stimulated Raman spectroscopy
The versatile functions of fluorescent proteins (FPs) as fluorescence biomarkers depend on
their intrinsic chromophores interacting with the protein environment. Besides X-ray …
their intrinsic chromophores interacting with the protein environment. Besides X-ray …
Chemical control of excited-state reactivity of the anionic green fluorescent protein chromophore
NH List, CM Jones, TJ Martínez - Communications Chemistry, 2024 - nature.com
Controlling excited-state reactivity is a long-standing challenge in photochemistry, as a
desired pathway may be inaccessible or compete with other unwanted channels. An …
desired pathway may be inaccessible or compete with other unwanted channels. An …