[HTML][HTML] S100 proteins: Diagnostic and prognostic biomarkers in laboratory medicine

CW Heizmann - Biochimica et Biophysica Acta (BBA)-Molecular Cell …, 2019 - Elsevier
S100 proteins are members of the superfamily of Ca 2+-binding proteins characterized by
the specific Ca 2+-binding motif, the EF-hand. Proteins of this superfamily are of clinical use …

Ca2+-Binding Proteins of the EF-Hand Superfamily: Diagnostic and Prognostic Biomarkers and Novel Therapeutic Targets

CW Heizmann - Calcium-binding proteins of the EF-hand superfamily …, 2019 - Springer
A multitude of Ca 2+-sensor proteins containing the specific Ca 2+-binding motif (helix-loop-
helix, called EF-hand) are of major clinical relevance in a many human diseases …

A ten-gene signature-based risk assessment model predicts the prognosis of lung adenocarcinoma

H Jiang, S Xu, C Chen - BMC cancer, 2020 - Springer
Background Lung adenocarcinoma (LUAD) is a major cause of cancer death. Therefore,
identifying potential prognostic risk factors is critical to improve the survival of patients with …

Prognostic values of S100 family members in ovarian cancer patients

Y Bai, LD Li, J Li, X Lu - Bmc Cancer, 2018 - Springer
Objective Exhibiting high consistence in sequence and structure, S100 family members are
interchangeable in function and they show a wide spectrum of biological processes …

Thioredoxin-1 promotes colorectal cancer invasion and metastasis through crosstalk with S100P

F Lin, P Zhang, Z Zuo, F Wang, R Bi, W Shang, A Wu… - Cancer Letters, 2017 - Elsevier
Abstract Thioredoxin-1 (Trx-1) is a small redox-regulating protein, which plays an important
role in several cellular functions. Despite recent advances in understanding the biology of …

Calcium-binding protein S100P promotes tumor progression but enhances chemosensitivity in breast cancer

Y Cong, Y Cui, S Wang, L Jiang, J Cao, S Zhu… - Frontiers in …, 2020 - frontiersin.org
Background Chemoresistance remains one of the obstacles to overcome in the treatment of
breast cancer. S100 calcium-binding protein P (S100P) has been observed to be …

Molecular changes during extended neoadjuvant letrozole treatment of breast cancer: distinguishing acquired resistance from dormant tumours

C Selli, AK Turnbull, DA Pearce, A Li, A Fernando… - Breast Cancer …, 2019 - Springer
Background The risk of recurrence for endocrine-treated breast cancer patients persists for
many years or even decades following surgery and apparently successful adjuvant therapy …

Retracted: Downregulation of Long Noncoding RNA HOTAIR and EZH2 Induces Apoptosis and Inhibits Proliferation, Invasion, and Migration of Human Breast …

L Han, HC Zhang, L Li, CX Li, X Di… - Cancer Biotherapy & …, 2018 - liebertpub.com
Cancer Biotherapy and Radiopharmaceuticals officially retracts the article entitled,“
Downregulation of Long Noncoding RNA HOTAIR and EZH2 Induces Apoptosis and Inhibits …

[HTML][HTML] High FOXA1 levels induce ER transcriptional reprogramming, a pro-metastatic secretome, and metastasis in endocrine-resistant breast cancer

X Fu, R Pereira, CC Liu, C De Angelis, MJ Shea… - Cell Reports, 2023 - cell.com
Aberrant activation of the forkhead protein FOXA1 is observed in advanced hormone-related
cancers. However, the key mediators of high FOXA1 signaling remain elusive. We …

Associations of serum S100B and S100P with the presence and classification of diabetic peripheral neuropathy in adults with type 2 diabetes: a case-cohort study

M Afarideh, VZ Esteghamati, M Ganji, B Heidari… - Canadian Journal of …, 2019 - Elsevier
Objectives Novel biomarkers of diabetic peripheral neuropathy provide potentially useful
information for early identification and treatment of diabetic neuropathy, ultimately serving to …