Manganese (Mn) is an essential micronutrient required for the normal development of many
organs, including the brain. Although its roles as a cofactor in several enzymes and in …

Alzheimer's disease and related dementias lack effective treatment or cures and are major
public health challenges. Risk for Alzheimer's disease and related dementias is partially …

Alzheimer's disease (AD) is the most common form of dementia, which is progressively
affecting elderly people. The dyshomeostasis of biometals and accumulation of toxic metals …

Amyloid and tau aggregation are implicated in manifold neurodegenerative diseases and
serve as two signature pathological hallmarks in Alzheimer's disease (AD). Though aging is …

Alterations in the concentrations of trace elements may play a vital role in Alzheimer
dementia progression. However, previous research results are inconsistent, and there is still …

In addition to the devastating symptoms of dementia, Alzheimer's disease (AD) is
characterized by accumulation of the processing products of the amyloid-β (Aβ) peptide …

Nanotechnology is the most promising technology to evolve in the last decade. Recent
research has shown that transition metal nanoparticles especially manganese (Mn)-based …

Understanding of the immediate mechanisms of Mn-induced neurotoxicity is rapidly
evolving. We seek to provide a summary of recent findings in the field, with an emphasis to …

Manganese (Mn) is an essential trace element with unique functions in the body; it acts as a
cofactor for many enzymes involved in energy metabolism, the endogenous antioxidant …

Neurodegenerative processes encompass a large variety of diseases with different
pathological patterns and clinical features, such as Alzheimer's and Parkinson's diseases …