Biocatalytic cascades are a powerful tool for building complex molecules containing oxygen
and nitrogen functionalities. Moreover, the combination of multiple enzymes in one pot offers …

With recent outbreaks of COVID-19 and Ebola, health and healthcare have once more
shown to be heavily burdened by the lack of generally effective anti-viral therapies. Initial …

Nitrogen-containing heterocycles (N-heterocycles) are ubiquitous in both organisms and
pharmaceutical products. Biocatalysts are providing green approaches for synthesizing …

Biocatalysis-based synthesis can provide a sustainable and clean platform for producing
chemicals. Many oxidative biocatalytic routes require the cofactor NAD+ as an electron …

O 2-dependent biocatalysts are among the most studied and used biocatalysts on the lab
scale. Their diversity and functional versatility make them very attractive for the sustainable …

Light‐driven biotransformations in recombinant cyanobacteria allow to employ
photosynthetic water‐splitting for cofactor‐regeneration and thus, to save the use of organic …

We have developed a scalable platform that employs electrolysis for an in vitro synthetic
enzymatic cascade in a continuous flow reactor. Both H2 and O2 were produced by …

D-Amino acids are key intermediates required for the synthesis of important
pharmaceuticals. However, establishing a universal enzymatic method for the general …

To study metalloenzymes in detail, we developed a new experimental setup allowing the
controlled preparation of catalytic intermediates for characterization by various …

The NAD+-reducing soluble [NiFe] hydrogenase (SH) is the key enzyme for production and
consumption of molecular hydrogen (H 2) in Synechocystis sp. PCC6803. In this study, we …