ISWI chromatin remodeling complexes recruit NSD2 and H3K36me2 in pericentromeric heterochromatin

N Goto, K Suke, N Yonezawa, H Nishihara… - Journal of Cell …, 2024 - rupress.org
Histone H3 lysine36 dimethylation (H3K36me2) is generally distributed in the gene body
and euchromatic intergenic regions. However, we found that H3K36me2 is enriched in …

Stalling out chromatin machinery—Oncohistone mutation disrupts heterochromatin memory

SR Wasserman, NA Hathaway - Molecular Cell, 2024 - cell.com
In this issue, Sinha et al. 1 use cellular chromatin reporter assays along with CRISPR gene
editing to reveal that the histone H3. 3K36M oncohistone mutation disrupts epigenetic …

EasyFlow: An open-source, user-friendly cytometry analyzer with graphic user interface (GUI)

Y Ma, I Eizenberg-Magar, Y Antebi - PloS one, 2024 - journals.plos.org
Flow cytometry enables quantitative measurements of fluorescence in single cells. The
technique was widely used for immunology to identify populations with different surface …

Precision epigenetic editing: Technological advances, enduring challenges, and therapeutic applications

GV Roth, IR Gengaro, LS Qi - Cell Chemical Biology, 2024 - cell.com
The epigenome is a complex framework through which gene expression is precisely and
flexibly modulated to incorporate heritable memory and responses to environmental stimuli …